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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/41153
Title: Incidence of and risk factors for acute respiratory distress syndrome in patients admitted to surgical intensive care units: The multicenter thai university-based surgical intensive care unit (THAI-SICU) study
Authors: Onuma Chaiwat
Kaweesak Chittawatanarat
Annop Piriyapathsom
Chawika Pisitsak
Thammasak Thawitsri
Sunisa Chatmongkolchart
Suneerat Kongsayreepong
Mahidol University
Chiang Mai University
King Chulalongkorn Memorial Hospital, Faculty of Medicine Chulalongkorn University
Prince of Songkla University
Keywords: Medicine
Issue Date: 1-Sep-2016
Citation: Journal of the Medical Association of Thailand. Vol.99, No.9 (2016), S118-S127
Abstract: © 2016, Medical Association of Thailand. All rights reserved. Objective: The incidence and outcomes of acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) are unclear. We evaluated the cumulative incidence of, risk factors for, and outcomes of ALI/ARDS in surgical ICUs (SICUs). Material and Method: The multicenter Thai University-based Surgical Intensive Care Unit (THAI-SICU) study was a prospective, observational cohort study including nine university-based SICUs throughout Thailand from April 2011 to January 2013. All >18-year-old surgical patients who were admitted to general SICUs were recruited. The primary outcome was the incidence of ALI/ARDS. Results: In total, 4,652 patients were analyzed. ALI/ARDS new developed in 114 patients (2.5%). Patients with ALI/ARDS had higher APACHE II (20.0 vs. 11.4, respectively; p<0.001) and SOFA scores (7.3 vs. 3.1, respectively; p<0.001) and a higher incidence of past or current smoking (48% vs. 36%, respectively; p<0.001) than the non-ARDS patients. The 28-day mortality rate was significantly higher in patients with than without ALI/ARDS (50% vs. 12%; p<0.001). Higher APACHE II and SOFA scores and higher rates of current or past smoking were independent predictors of ALI/ARDS. Conclusion: The incidence of ALI/ARDS in the THAI-SICU study was low, but the mortality rate was high. Higher severity scores and smoking were associated with ALI/ARDS.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85012181029&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/41153
ISSN: 01252208
Appears in Collections:Scopus 2016-2017

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