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Title: Cost of rotavirus diarrhea for programmatic evaluation of vaccination in Vietnam
Authors: Arthorn Riewpaiboon
Sunheang Shin
Thi Phuong Mai Le
Dinh Thiem Vu
Thi Hien Anh Nguyen
Neal Alexander
Duc Anh Dang
Le Huu Tho
Vu Thi Thuy
Ta Van Chan
Phu Quoc Viet
Nguyen Minh Nguyet
Le Thi Hoa
Mahidol University
London School of Hygiene & Tropical Medicine
International Vaccine Institute, Seoul
National Institute of Hygiene and Epidemiology
Keywords: Medicine
Issue Date: 11-Aug-2016
Citation: BMC Public Health. Vol.16, No.1 (2016)
Abstract: © 2016 The Author(s). Background: Rotavirus is the most common etiology of diarrhea-associated hospitalizations and clinic visits in Vietnamese children < 5 years old. To estimate the economic burden of rotavirus-associated formal healthcare encounters, an economic study was conducted. Methods: A cost-of-illness study was performed from a societal perspective. Data were collected from children below the age of five years who presented to a clinic or hospital with symptoms of acute gastroenteritis (AGE). Patient-specific information on resource use and cost was obtained through caregiver interviews and medical chart review. Costs are presented in 2014 US dollar ($). Results: A total of 557 children with symptoms of AGE were enrolled from March through June 2009, with mean age of 16.5 months. Of the 340 outpatients and 217 admitted patients enrolled, 41 % tested rotavirus positive. It was found that, from a societal perspective, the mean total cost of AGE was $175. Costs of patients with and without rotavirus were $217 and $158, respectively. From multiple regression analysis, it was found that rotavirus infection, patient age and receiving oral rehydration solution before visiting health facility had significant effect on the costs. Conclusions: This study clearly demonstrated substantial economic burden of AGE including rotavirus disease. They were significantly greater than the previously reported cost estimates in Vietnam. These updated costs of illness result in more favorable vaccine cost-effectiveness than in previous economic evaluations.
ISSN: 14712458
Appears in Collections:Scopus 2016-2017

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