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Title: Bone status measured by quantitative ultrasound: A comparison with DXA in Thai children
Authors: W. Srichan
W. Thasanasuwan
K. Kijboonchoo
N. Rojroongwasinkul
W. Wimonpeerapattana
I. Khouw
P. Deurenberg
Mahidol University
Friesland Campina
Nutrition Consultant
Keywords: Medicine
Issue Date: 1-Aug-2016
Citation: European Journal of Clinical Nutrition. Vol.70, No.8 (2016), 894-897
Abstract: © 2016 Macmillan Publishers Limited. All rights reserved. Background/Objectives:Quantitative ultrasound (QUS) is used to measure bone quality and is known to be safe, radiation free and relatively inexpensive compared with dual-energy X-ray absorptiometry (DXA) that is considered the gold standard for bone status assessments. However, there is no consensus regarding the validity of QUS for measuring bone status. The aim of this study was to compare QUS and DXA in assessing bone status in Thai children.Subjects/Methods:A total of 181 Thai children (90 boys and 91 girls) aged 6 to 12 years were recruited. Bone status was measured by two different techniques in terms of the speed of sound (SOS) using QUS and bone mineral density (BMD) using DXA. Calcium intake was assessed by 24 h diet recall. Pearson's correlation, κ-statistic and Bland and Altman analysis were used to assess the agreement between the methods.Results:There was no correlation between the two different techniques. Mean difference (s.d.) of the Z-scores of BMD and SOS was-0.61 (1.27) that was different from zero (P<0.05). Tertiles of Z-scores of BMD and QUS showed low agreement (κ 0.022, P=0.677) and the limits of agreement in Bland and Altman statistics were wide.Conclusions:Although QUS is easy and convenient to use, the SOS measurements at the radius seem not appropriate for assessing bone quality status.
ISSN: 14765640
Appears in Collections:Scopus 2016-2017

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