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Title: Polycythemia vera concomitant with renal angiomyolipoma: Case report and clinical outcome
Authors: Supat Chamnanchanunt
Pravinwan Thungthong
Niphon Praditphol
Kunapa Iam-Arunthai
Jirapong Dowreang
Chajchawan Nakhakes
Tawatchai Suwanban
Mahidol University
Rajavithi Hospital
Keywords: Biochemistry, Genetics and Molecular Biology
Issue Date: 1-Feb-2017
Citation: Asian Biomedicine. Vol.11, No.1 (2017), 89-92
Abstract: Background: Polycythemia vera has been found in a wide range of hematopoietic tissue disorders, but rarely concomitant with renal abnormality. To our knowledge there is only one available report of a patient with polycythemia vera concomitant with renal angiomyolipoma, and the report does not cover the clinical course of this rare finding. Objectives: To report the presentation and clinical course of a patient with polycythemia vera concomitant with right renal angiomyolipoma. Methods: We retrospectively reviewed the medical records of a patient with polycythemia vera who presented with renal angiomyolipoma. Results: Our patient presented with a right renal mass and polycythemia vera diagnosed by a point mutation in the gene for Janus kinase 2. The mass was diagnosed as renal angiomyolipoma on histopathology. After partial nephrectomy, she was prescribed a low dosage of hydroxyurea without the return of erythrocytosis for a year. Conclusions: Polycythemia vera responded well to low dosage hydroxyurea, which controlled erythrocytosis after removing the renal mass.
ISSN: 1875855X
Appears in Collections:Scopus 2016-2017

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