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Title: Lanostane triterpenoids from the edible mushroom Astraeus asiaticus
Authors: Masahiko Isaka
Somporn Palasarn
Sujinda Sommai
Sukitaya Veeranondha
Kitlada Srichomthong
Palangpon Kongsaeree
Samran Prabpai
Thailand National Center for Genetic Engineering and Biotechnology
Mahidol University
Keywords: Biochemistry, Genetics and Molecular Biology;Chemistry
Issue Date: 1-Jan-2017
Citation: Tetrahedron. Vol.73, No.12 (2017), 1561-1567
Abstract: © 2017 Elsevier Ltd Seven new lanostane triterpenoids, astraeusins M–Q (1–5), 26-epi-artabotryol C1 (6), and 26-epi-astrasiaone (7), together with seventeen known compounds (8–24), were isolated from the food mushroom Astraeus asiaticus. The C-26 configuration of artabotriol C1 and astrasiaone, originally reported as 26R (6 and 7, respectively), was revised to be 26S (16 and 17, respectively). Astraeusin M (1) exhibited antimalarial activity against Plasmodium falciparum K1 with an IC50value of 3.0 μg/mL.
ISSN: 14645416
Appears in Collections:Scopus 2016-2017

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