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|Title:||Cytotoxic tropolones from the fungus Nemania sp. BCC 30850|
Thailand National Center for Genetic Engineering and Biotechnology
|Keywords:||Biochemistry, Genetics and Molecular Biology;Chemistry|
|Citation:||Tetrahedron. Vol.73, No.25 (2017), 3505-3512|
|Abstract:||© 2017 Elsevier Ltd Twelve new compounds, including nine tropolones, nemanolones A−I (1–9), three 7-isochromenones, nemanecins A−C (10–12), and a new naturally isolated 4-isochromanone (13), along with two known compounds, 7,8-dihydroxy-3-methyl isochroman-4-one (XJP), and chaetoquadrin F, were isolated from culture broth of the fungus Nemania sp. BCC 30850. Structures of these compounds were elucidated by NMR and MS spectroscopic analyses. Nemanolones exhibited cytotoxic activities and two of them, compounds 1 and 2, also showed antibacterial activity against Bacillus cereus and antifungal activity against Candida albicans.|
|Appears in Collections:||Scopus 2016-2017|
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