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dc.contributor.authorMyo Thiha Zawen_US
dc.contributor.authorMyo Thanten_US
dc.contributor.authorTin Maung Hlaingen_US
dc.contributor.authorNaing Zin Aungen_US
dc.contributor.authorMin Thuen_US
dc.contributor.authorKanit Phumchueaen_US
dc.contributor.authorKanokwan Phusrien_US
dc.contributor.authorTeerawat Saeseuen_US
dc.contributor.authorRitthideach Yorsaengen_US
dc.contributor.authorWang Nguitragoolen_US
dc.contributor.authorIngrid Felgeren_US
dc.contributor.authorJaranit Kaewkungwalen_US
dc.contributor.authorLiwang Cuien_US
dc.contributor.authorJetsumon Sattabongkoten_US
dc.contributor.otherDefence Services Medical Research Centre (DSMRC)en_US
dc.contributor.otherLoikaw Military Hospitalen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherSwiss Tropical and Public Health Institute (Swiss TPH)en_US
dc.contributor.otherPennsylvania State Universityen_US
dc.identifier.citationMalaria Journal. Vol.16, No.1 (2017)en_US
dc.description.abstract© 2017 The Author(s). Background: Myanmar has the heaviest burden of malaria in the Greater Mekong Sub-region. Asymptomatic Plasmodium spp. infections are common in this region and may represent an important reservoir of transmission that must be targeted for malaria elimination. Methods: A mass blood survey was conducted among 485 individuals from six villages in Kayah State, an area of endemic but low transmission malaria in eastern Myanmar. Malaria infection was screened by rapid diagnostic test (RDT), light microscopy and real-time polymerase chain reaction (PCR), and its association with demographic factors was explored. Results: The prevalence of asymptomatic Plasmodium spp. infection was 2.3% (11/485) by real-time PCR. Plasmodium vivax accounted for 72.7% (8/11) and Plasmodium falciparum for 27.3% (3/11) of infections. Men were at greater risk of infection by Plasmodium spp. than women. Individuals who worked as farmers or wood and bamboo cutters had an increased risk of infection. Conclusion: A combination of RDT, light microscopy and PCR diagnostics were used to identify asymptomatic malaria infection, providing additional information on asymptomatic cases in addition to the routine statistics on symptomatic cases, so as to determine the true burden of disease in the area. Such information and risk factors can improve malaria risk stratification and guide decision-makers towards better design and delivery of targeted interventions in small villages, representative of Kayah State.en_US
dc.rightsMahidol Universityen_US
dc.subjectImmunology and Microbiologyen_US
dc.titleAsymptomatic and sub-microscopic malaria infection in Kayah State, eastern Myanmaren_US
Appears in Collections:Scopus 2016-2017

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