Please use this identifier to cite or link to this item:
Title: Cytotoxic lanostanes from fruits of Garcinia wallichii Choisy (Guttiferae)
Authors: Sakchai Hongthong
Jatuporn Meesin
Phanruethai Pailee
Darunee Soorukram
Palangpon Kongsaeree
Samran Prabpai
Pawinee Piyachaturawat
Surawat Jariyawat
Kanoknetr Suksen
Thaworn Jaipetch
Narong Nuntasaen
Vichai Reutrakul
Chutima Kuhakarn
Mahidol University
Chulabhorn Research Institute
National Park, Wildlife and Plant Conservation Department, Thailand
Keywords: Biochemistry, Genetics and Molecular Biology;Chemistry
Issue Date: 1-Jan-2016
Citation: Bioorganic and Medicinal Chemistry Letters. Vol.26, No.23 (2016), 5773-5779
Abstract: © 2016 Elsevier Ltd Five new lanostanes, wallichinanes A–E (1–5) together with a known lanostane derivative 6 were isolated from the cytotoxic hexanes extract of fruits of Garcinia wallichii Choisy (Guttiferae). The structures of the isolated compounds were established by analysis of spectroscopic data, X-ray diffraction technique as well as comparison with the literature data. The cytotoxicity of all isolated compounds against a panel of cultured cancer cell lines was evaluated. Compound 4 exhibited good cytotoxicity with ED50values ranging from 3.91 to 7.63 μM.
ISSN: 14643405
Appears in Collections:Scopus 2016-2017

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.