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Title: Use of Xylazine in Drug-Facilitated Crimes
Authors: Jatupon Krongvorakul
Saranya Auparakkitanon
Satariya Trakulsrichai
Pitsucha Sanguanwit
Jetjamnong Sueajai
Nantida Noumjad
Winai Wananukul
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Keywords: Biochemistry, Genetics and Molecular Biology;Medicine
Issue Date: 1-Jul-2018
Citation: Journal of Forensic Sciences. Vol.63, No.4 (2018), 1325-1330
Abstract: © 2017 American Academy of Forensic Sciences Human xylazine poisoning is uncommon. This report describes the use of xylazine for intentional poisoning with criminal intent. Two incidents occurred within 3 weeks: the first involved one victim, and the second involved two victims. The clinical presentations were brief coma, bradycardia, hypotension, and hyperglycemia. The victims recalled having been given a drink from a stranger in a hospital waiting room before loss of consciousness. In the first case, general drug screening by gas chromatography/mass spectrometry (MS) revealed xylazine in the gastric contents, but liquid chromatography–tandem MS (LC-MS/MS) of serum did not. In the second incident, LC-MS/MS screening of both victims’ urine and serum samples revealed an unknown peak in the total ion chromatograms, which a molecular mass database identified as morantel or xylazine. The latter was confirmed by comparison with a xylazine standard. Based on this report, we suggest that xylazine should be classified as a controlled drug.
ISSN: 15564029
Appears in Collections:Scopus 2018

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