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Title: Spatiotemporal Bayesian networks for malaria prediction
Authors: Peter Haddawy
A. H.M.Imrul Hasan
Rangwan Kasantikul
Saranath Lawpoolsri
Patiwat Sa-angchai
Jaranit Kaewkungwal
Pratap Singhasivanon
Mahidol University
Keywords: Computer Science;Medicine
Issue Date: 1-Jan-2018
Citation: Artificial Intelligence in Medicine. Vol.84, (2018), 127-138
Abstract: © 2017 Elsevier B.V. Targeted intervention and resource allocation are essential for effective malaria control, particularly in remote areas, with predictive models providing important information for decision making. While a diversity of modeling technique have been used to create predictive models of malaria, no work has made use of Bayesian networks. Bayes nets are attractive due to their ability to represent uncertainty, model time lagged and nonlinear relations, and provide explanations. This paper explores the use of Bayesian networks to model malaria, demonstrating the approach by creating village level models with weekly temporal resolution for Tha Song Yang district in northern Thailand. The networks are learned using data on cases and environmental covariates. Three types of networks are explored: networks for numeric prediction, networks for outbreak prediction, and networks that incorporate spatial autocorrelation. Evaluation of the numeric prediction network shows that the Bayes net has prediction accuracy in terms of mean absolute error of about 1.4 cases for 1 week prediction and 1.7 cases for 6 week prediction. The network for outbreak prediction has an ROC AUC above 0.9 for all prediction horizons. Comparison of prediction accuracy of both Bayes nets against several traditional modeling approaches shows the Bayes nets to outperform the other models for longer time horizon prediction of high incidence transmission. To model spread of malaria over space, we elaborate the models with links between the village networks. This results in some very large models which would be far too laborious to build by hand. So we represent the models as collections of probability logic rules and automatically generate the networks. Evaluation of the models shows that the autocorrelation links significantly improve prediction accuracy for some villages in regions of high incidence. We conclude that spatiotemporal Bayesian networks are a highly promising modeling alternative for prediction of malaria and other vector-borne diseases.
ISSN: 18732860
Appears in Collections:Scopus 2018

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