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|Title:||Effect of antiretroviral therapy on plasma concentrations of chloroquine and desethyl-chloroquine|
|Authors:||Matthew M. Ippolito|
Jeffrey M. Jacobson
Michael M. Lederman
Theresa A. Shapiro
Nuffield Department of Clinical Medicine
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins University
Case Western Reserve University
|Citation:||Clinical Infectious Diseases. Vol.67, No.10 (2018), 1617-1620|
|Abstract:||© The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. The effect of antiretroviral therapy (ART) on chloroquine and desethyl-chloroquine plasma concentrations was evaluated in clinical trial participants. Concentrations did not differ among participants receiving protease inhibitor-based ART (n = 9), efavirenz-based ART (n = 15), or other ART (n = 8) and those not receiving ART (n = 31). Efavirenz seemed to inhibit chloroquine desethylation.|
|Appears in Collections:||Scopus 2018|
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