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Title: C-reactive protein point of care testing in the management of acute respiratory infections in the Vietnamese primary healthcare setting - A cost benefit analysis
Authors: Yoel Lubell
Nga T.T. Do
Kinh V. Nguyen
Ngan T.D. Ta
Ninh T.H. Tran
Hung M. Than
Long B. Hoang
Poojan Shrestha
Rogier H. Van Doorn
Behzad Nadjm
Heiman F.L. Wertheim
University of Oxford
Mahidol University
Nuffield Department of Clinical Medicine
Radboudumc Center for Infectious Diseases (RCI)
National Hospital for Tropical Diseases
Oxford University Clinical Research Unit
Keywords: Medicine
Issue Date: 4-Oct-2018
Citation: Antimicrobial Resistance and Infection Control. Vol.7, No.1 (2018)
Abstract: © 2018 The Author(s). Aim: We assess the cost-benefit implications of C-reactive protein (CRP) testing in reducing antibiotic prescription for acute respiratory infection in Viet Nam by comparing the incremental costs of CRP testing with the economic costs of antimicrobial resistance averted due to lower antibiotic prescribing. Findings: Patients in the CRP group and the controls incurred similar costs in managing their illness, excluding the costs of the quantitative CRP tests, provided free of charge in the trial context. Assuming a unit cost of $1 per test, the incremental cost of CRP testing was $0.93 per patient. Based on a previous modelling analysis, the 20 percentage point reduction in prescribing observed in the trial implies a societal benefit of $0.82 per patient. With the low levels of adherence to the test results observed in the trial, CRP testing would not be cost-beneficial. The sensitivity analyses showed, however, that with higher adherence to test results their use would be cost-beneficial.
ISSN: 20472994
Appears in Collections:Scopus 2018

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