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Title: Do we need perioperative pharmacogenetic testing?
Authors: Sirirat Rattana-Arpa
Patcharee Sriswasdi
Faculty of Medicine, Siriraj Hospital, Mahidol University
Keywords: Medicine
Issue Date: 1-Sep-2018
Citation: Journal of the Medical Association of Thailand. Vol.101, No.9 (2018), S159-S166
Abstract: © 2018, Medical Association of Thailand. All rights reserved. Multiple drugs with various mechanisms of actions are used simultaneously during anesthetic practice. Even if the same dose of drug is administered, diverse individual responses usually occur. These different responses might relate to their pharmacogenetics variation. The pharmacogenetics research network has established a pharmacogenetics knowledge base in order to collect, encode, and disseminate knowledge about the impact of human genetic variations on drug response. For perioperative period, opioids are the common drugs used with various individual responses. This review shows the pharmacogenetic aspects of four common opioids: morphine, fentanyl, codeine and oxycodone, and their future trends for perioperative pharmacogenetic testing.
ISSN: 01252208
Appears in Collections:Scopus 2018

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