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Title: Multiple myeloma concealed by adrenal Cushing syndrome: A case report and review of the literature
Authors: Taweesak Wannachalee
Nuttagarn Jantanapornchai
Kittima Suphadirekkul
Sirinart Sirinvaravong
Weerapat Owattanapanich
Faculty of Medicine, Siriraj Hospital, Mahidol University
Sena Hospital
Keywords: Medicine
Issue Date: 13-Aug-2018
Citation: Journal of Medical Case Reports. Vol.12, No.1 (2018)
Abstract: © 2018 The Author(s). Background: Cushing syndrome coexisting with multiple myeloma has been previously described in a few reports. Overlapping clinical manifestations can lead to misdiagnoses. Case presentation: We presented an extremely rare case of a 33-year-old Thai woman with concomitant kappa light chain myeloma with adrenal Cushing syndrome, both of which were related to skeletal manifestations. A precedence report indicated that treatment of the Cushing syndrome could exacerbate the myeloma symptoms. Therefore, we were faced with the dilemma of which disease should be addressed first. We decided to treat our patient with a combination chemotherapy followed by an autologous stem cell transplant. Subsequently, a left laparoscopic adrenalectomy was successfully undertaken. Conclusion: We have reported the first association between adrenocorticotropic hormone-independent Cushing syndrome resulting from a left autonomous cortisol-secreting adrenal adenoma, and multiple myeloma.
ISSN: 17521947
Appears in Collections:Scopus 2018

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