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dc.contributor.authorPattara Rattanawongen_US
dc.contributor.authorJirat Chenbhanichen_US
dc.contributor.authorWasawat Vutthikraiviten_US
dc.contributor.authorPakawat Chongsathidkieten_US
dc.contributor.otherDuke University Medical Centeren_US
dc.contributor.otherTexas Tech University at Lubbocken_US
dc.contributor.otherFaculty of Medicine, Ramathibodi Hospital, Mahidol Universityen_US
dc.contributor.otherUniversity of Hawaii at Manoaen_US
dc.contributor.otherMetroWest Medical Centeren_US
dc.date.accessioned2019-08-28T06:16:26Z-
dc.date.available2019-08-28T06:16:26Z-
dc.date.issued2018-04-01en_US
dc.identifier.citationJournal of Atrial Fibrillation. Vol.10, No.6 (2018), 1-7en_US
dc.identifier.issn19416911en_US
dc.identifier.other2-s2.0-85052407683en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85052407683&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/46798-
dc.description.abstract© 2018 American Society for Enology and Viticulture. All rights reserved. Background: Recent studies suggested that variants on chromosome loci 4q25, 1q21, and 16q22 were associated with atrial fibrillation recurrence after catheter ablation. In this study, we performed a systematic review and meta-analysis to explore the association between variants on chromosome loci 4q25, 1q21, and 16q22 and atrial fibrillation recurrence after catheter ablation. Methods: We comprehensively searched the databases of MEDLINE and EMBASE from inception to January 2017. Included studies were published prospective or retrospective cohort and case control studies that compared the risk of atrial fibrillation recurrence after catheter ablation in AF patients with chromosome 4q25, 1q21, and 16q22 variants versus no variants. Single-nucleotide polymorphism rs1906617, rs2106261, rs7193343, rs2200733, rs10033464, rs13376333, and rs6843082 were included in this analysis. Data from each study were combined using the random-effects, generic inverse variance method of DerSimonian and Laird to calculate the risk ratios and 95% confidence intervals. Results: Seven studies from January 2010 to June 2017 involving 3,322 atrial fibrillation patients were included in this meta-analysis. According to the pooled analysis, there was a strong independent association between chromosome 4q25 variant (rs2200733) and the risk of atrial fibrillation recurrence after catheter ablation (risk ratio 1.45 [95% confidence interval 1.15-1.83], P = 0.002). No association was found in other variants. Conclusion: Our meta-analysis demonstrates a statistically significant increased risk of atrial fibrillation recurrence after catheter ablation in 4q25 variant (only in rs2200733) but not in 1q21 or 16q22 variants.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85052407683&origin=inwarden_US
dc.subjectMedicineen_US
dc.titleA chromosome 4q25 variant is sssociated with atrial fibrillation recurrence after catheter ablation: A systematic review and meta-analysisen_US
dc.typeReviewen_US
dc.rights.holderSCOPUSen_US
Appears in Collections:Scopus 2018

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