Simple jQuery Dropdowns
Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/47043
Title: The teratogenic effects of monosodium glutamate (MSG) on the development of chick embryos
Authors: Jantima Roongruangchai
Yadaridee Viravud
Vasana Plakornkul
Kesorn Sripaoraya
Wanida Boonmark
Kosol Roongruangchai
Faculty of Medicine, Siriraj Hospital, Mahidol University
Keywords: Medicine
Issue Date: 1-Jan-2018
Citation: Siriraj Medical Journal. Vol.70, No.6 (2018), 514-522
Abstract: © 2018 Siriraj Medical Journal. Objective: The present study was conducted to evaluate the toxicity and teratogenic effects of MSG in chick embryo development. Methods: Various concentrations of MSG solution, 1 mg, 1.5 mg, 2.5 mg and 3 mg of MSG/gm egg weight were injected into the fertilized hen's egg at 21 hrs of incubation and further incubated until day 3, 6 and 10. The day 3 and day 6 were processed for serial section, while the day 3 was processed for total mount and day 10 were observed totally. Results: The effects of MSG were growth retardation, embryonic death and congenital malformations of several organs such as brain (rachischisis and anencephaly), eye (microphthalmia and anophthalmia), ectopiacordis, ectopia viscera, opening of posterior neuropore (spinal bifida) and under development of heart and viscerae. Conclusion: MSG produced congenital deformities and growth retardation in chick embryos which may predict to cause the same results to human embryos. Pregnant women should be advised not to consume MSG to avoid potential harmful effects to the unborn child.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85059526438&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/47043
ISSN: 22288082
Appears in Collections:Scopus 2018

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.