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dc.contributor.authorSukonthar Ngampramuanen_US
dc.contributor.authorPuttichai Tungtongen_US
dc.contributor.authorSujira Mukdaen_US
dc.contributor.authorApichat Jariyavilasen_US
dc.contributor.authorChanin Sakulisariyapornen_US
dc.contributor.otherSrithanya Hospitalen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherSrinakharinwirot Universityen_US
dc.date.accessioned2019-08-28T06:36:55Z-
dc.date.available2019-08-28T06:36:55Z-
dc.date.issued2018-01-01en_US
dc.identifier.citationDepression Research and Treatment. Vol.2018, (2018)en_US
dc.identifier.issn2090133Xen_US
dc.identifier.issn20901321en_US
dc.identifier.other2-s2.0-85045690070en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85045690070&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/47192-
dc.description.abstract© 2018 Sukonthar Ngampramuan et al. Major depressive disorder (MDD) is associated with changes in autonomic nervous system (ANS) and cognitive impairment. Heart rate variability (HRV) and Pulse pressure (PP) parameters reflect influences of the sympathetic and parasympathetic nervous system. Cortisol exerts its greatest effect on the hippocampus, a brain area closely related to cognitive function. This study aims to examine the effect of HRV, PPG, salivary cortisol levels, and cognitive function in MDD patients by using noninvasive techniques. We have recruited MDD patients, diagnosed based on DSM-V-TR criteria compared with healthy control subjects. Their HRV and PP were measured by electrocardiogram (ECG) and photoplethysmography (PPG). Salivary cortisol levels were collected and measured on the same day. MDD patients exhibited elevated values of mean HR, standard deviation of HR (SDHR), low frequency (LF) power, low frequency/high frequency (LF/HF) ratio, mean PP, standard deviation of pulse pressure (SDPP), and salivary cortisol levels. Simultaneously, they displayed lower values of mean of R-R intervals (mean NN), standard deviation of R-R intervals (SDNN), high frequency (HF) power, and WCST scores. Results have shown that the ANS of MDD patients were dominated by the sympathetic activity and that they have cognitive deficits especially in the domain of executive functioning.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85045690070&origin=inwarden_US
dc.subjectMedicineen_US
dc.subjectPsychologyen_US
dc.titleEvaluation of Autonomic Nervous System, Saliva Cortisol Levels, and Cognitive Function in Major Depressive Disorder Patientsen_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.1155/2018/7343592en_US
Appears in Collections:Scopus 2018

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