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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/47232
Title: Novel tools for the surveillance and control of dengue: findings by the dengueTools research consortium
Authors: Annelies Wilder-Smith
Hasitha Tissera
Sazaly AbuBakar
Pattamaporn Kittayapong
James Logan
Andreas Neumayr
Joacim Rocklöv
Peter Byass
Valérie R. Louis
Yesim Tozan
Eduardo Massad
Raman Preet
Ministry of Health Colombo
Fundacao Getulio Vargas
London School of Hygiene & Tropical Medicine
Umeå Universitet
University of Malaya
Swiss Tropical and Public Health Institute (Swiss TPH)
New York University
Universität Heidelberg
Mahidol University
Keywords: Medicine
Issue Date: 1-Jan-2018
Citation: Global Health Action. Vol.11, No.1 (2018)
Abstract: © 2018, © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Background: Dengue fever persists as a major global disease burden, and may increase as a consequence of climate change. Along with other measures, research actions to improve diagnosis, surveillance, prevention, and predictive models are highly relevant. The European Commission funded the DengueTools consortium to lead a major initiative in these areas, and this review synthesises the outputs and findings of this work conducted from 2011 to 2016. Research areas: DengueTools organised its work into three research areas, namely [1] Early warning and surveillance systems; [2] Strategies to prevent dengue in children; and [3] Predictive models for the global spread of dengue. Research area 1 focused on case-studies undertaken in Sri Lanka, including developing laboratory-based sentinel surveillance, evaluating economic impact, identifying drivers of transmission intensity, evaluating outbreak prediction capacity and developing diagnostic capacity. Research area 2 addressed preventing dengue transmission in school children, with case-studies undertaken in Thailand. Insecticide-treated school uniforms represented an intriguing potential approach, with some encouraging results, but which were overshadowed by a lack of persistence of insecticide on the uniforms with repeated washing. Research area 3 evaluated potential global spread of dengue, particularly into dengue-naïve areas such as Europe. The role of international travel, changing boundaries of vectors, developing models of vectorial capacity under different climate change scenarios and strategies for vector control in outbreaks was all evaluated. Concluding remarks: DengueTools was able to make significant advances in methods for understanding and controlling dengue transmission in a range of settings. These will have implications for public health agendas to counteract dengue, including vaccination programmes. Outlook: Towards the end of the DengueTools project, Zika virus emerged as an unexpected epidemic in the central and southern America. Given the similarities between the dengue and Zika viruses, with vectors in common, some of the DengueTools thinking translated readily into the Zika situation.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85057765266&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/47232
ISSN: 16549880
Appears in Collections:Scopus 2018

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