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Title: SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation
Authors: Katie D. White
Riichiro Abe
Michael Ardern-Jones
Thomas Beachkofsky
Charles Bouchard
Bruce Carleton
James Chodosh
Ricardo Cibotti
Robert Davis
Joshua C. Denny
Roni P. Dodiuk-Gad
Elizabeth N. Ergen
Jennifer L. Goldman
James H. Holmes
Shuen Iu Hung
Mario E. Lacouture
Rannakoe J. Lehloenya
Simon Mallal
Teri A. Manolio
Robert G. Micheletti
Caroline M. Mitchell
Maja Mockenhaupt
David A. Ostrov
Rebecca Pavlos
Munir Pirmohamed
Elena Pope
Alec Redwood
Misha Rosenbach
Michael D. Rosenblum
Jean Claude Roujeau
Arturo P. Saavedra
Hajirah N. Saeed
Jeffery P. Struewing
Hirohiko Sueki
Chonlaphat Sukasem
Cynthia Sung
Jason A. Trubiano
Jessica Weintraub
Lisa M. Wheatley
Kristina B. Williams
Brandon Worley
Wen Hung Chung
Neil H. Shear
Elizabeth J. Phillips
Duke-NUS Medical School Singapore
National Yang-Ming University Taiwan
Chang Gung Memorial Hospital
Wake Forest University School of Medicine
Health Sciences Authority, Government of Singapore
Vanderbilt University Medical Center
Hospital for Sick Children University of Toronto
Massachusetts General Hospital
University of Ottawa, Canada
Showa University School of Medicine
Niigata University School of Medicine
The University of Alabama at Birmingham
University of Melbourne
Wake Forest University Baptist Medical Center
Universität Freiburg im Breisgau
University of Southampton
Universite Paris 12 Val de Marne
University of California, San Francisco
Technion - Israel Institute of Technology
University of Liverpool
Murdoch University
Children's Mercy Hospitals and Clinics
National Institute of Allergy and Infectious Diseases
Loyola University Medical Center
University of Toronto
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
University of Florida
National Human Genome Research Institute
The University of British Columbia
Food and Drug Administration
Memorial Sloan-Kettering Cancer Center
BC Children's Hospital
Uniformed Services University of the Health Sciences
University of Pennsylvania
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Austin Health
Groote Schuur Hospital
Harvard Medical School
University of Tennessee Health Science Center
Lackland Air Force Base
Keywords: Medicine
Issue Date: 1-Jan-2018
Citation: Journal of Allergy and Clinical Immunology: In Practice. Vol.6, No.1 (2018), 38-69
Abstract: © 2017 American Academy of Allergy, Asthma & Immunology Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a life-threatening, immunologically mediated, and usually drug-induced disease with a high burden to individuals, their families, and society with an annual incidence of 1 to 5 per 1,000,000. To effect significant reduction in short- and long-term morbidity and mortality, and advance clinical care and research, coordination of multiple medical, surgical, behavioral, and basic scientific disciplines is required. On March 2, 2017, an investigator-driven meeting was held immediately before the American Academy of Dermatology Annual meeting for the central purpose of assembling, for the first time in the United States, clinicians and scientists from multiple disciplines involved in SJS/TEN clinical care and basic science research. As a product of this meeting, this article summarizes the current state of knowledge and expert opinion related to SJS/TEN covering a broad spectrum of topics including epidemiology and pharmacogenomic networks; clinical management and complications; special populations such as pediatrics, the elderly, and pregnant women; regulatory issues and the electronic health record; new agents that cause SJS/TEN; pharmacogenomics and immunopathogenesis; and the patient perspective. Goals include the maintenance of a durable and productive multidisciplinary network that will significantly further scientific progress and translation into prevention, early diagnosis, and management of SJS/TEN.
ISSN: 22132198
Appears in Collections:Scopus 2018

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