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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/47502
Title: Genetic homogeneity of goat malaria parasites in Asia and Africa suggests their expansion with domestic goat host
Authors: Morakot Kaewthamasorn
Mika Takeda
Tawee Saiwichai
Jesse N. Gitaka
Sonthaya Tiawsirisup
Yuhei Imasato
Ehab Mossaad
Ali Sarani
Winai Kaewlamun
Manun Channumsin
Suchart Chaiworakul
Wichit Katepongpun
Surapong Teeveerapunya
Jarus Panthong
Dominic K. Mureithi
Saw Bawm
Lat Lat Htun
Mar Mar Win
Ahmed Ali Ismail
Abdalla Mohamed Ibrahim
Keisuke Suganuma
Hassan Hakimi
Ryo Nakao
Ken Katakura
Masahito Asada
Osamu Kaneko
Mount Kenya University
Rajamangala University of Technology system
University of Zabol
Sudan University of Science and Technology
Chulalongkorn University
Hokkaido University
Mahidol University
Nagasaki University
Obihiro University of Agriculture and Veterinary Medicine
Livestock Office of Phetchaburi Province
Livestock Office of Kaeng Krachan District
Abrar University Somalia
University of Veterinary Science
Keywords: Multidisciplinary
Issue Date: 1-Dec-2018
Citation: Scientific Reports. Vol.8, No.1 (2018)
Abstract: © 2018 The Author(s). Plasmodium was first identified in a goat in Angola in 1923, and only recently characterized by DNA isolation from a goat blood sample in Zambia. Goats were first domesticated in the Fertile Crescent approximately 10,000 years ago, and are now globally distributed. It is not known if the Plasmodium identified in African goats originated from parasites circulating in the local ungulates, or if it co-evolved in the goat before its domestication. To address this question, we performed PCR-based surveillance using a total of 1,299 goat blood samples collected from Sudan and Kenya in Africa, Iran in west Asia, and Myanmar and Thailand in southeast Asia. Plasmodium DNA was detected from all locations, suggesting that the parasite is not limited to Africa, but widely distributed. Whole mitochondrial DNA sequences revealed that there was only one nucleotide substitution between Zambian/Kenyan samples and others, supporting the existence of a goat-specific Plasmodium species, presumably Plasmodium caprae, rather than infection of goats by local ungulate malaria parasites. We also present the first photographic images of P. caprae, from one Kenyan goat sample.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85045404571&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/47502
ISSN: 20452322
Appears in Collections:Scopus 2018

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