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Title: Asymptomatic Histoplasma Pylephlebitis in an Orthotopic Liver Transplant Recipient: A Case Report and Literature Review
Authors: Pakpoom Phoompoung
Methee Chayakulkeeree
Popchai Ngamskulrungroj
Ananya Pongpaibul
Faculty of Medicine, Siriraj Hospital, Mahidol University
Keywords: Agricultural and Biological Sciences;Immunology and Microbiology
Issue Date: 15-Feb-2019
Citation: Mycopathologia. Vol.184, No.1 (2019), 177-180
Abstract: © 2018, Springer Science+Business Media B.V., part of Springer Nature. Histoplasma capsulatum is one of the most common pathogenic dimorphic fungi in Thailand. Its usual clinical syndrome is progressive disseminated histoplasmosis, whereas isolated hepatic histoplasmosis is extremely rare. Here, we report the world’s first reported case of hepatic histoplasmosis with pylephlebitis in a 45-year-old Thai male who underwent orthotopic liver transplantation due to hepatitis B cirrhosis. Histopathology of the recipient’s liver showed infiltration of fungal organisms in portal vein and hepatic granulomas. Serum H. capsulatum antibody was positive, and molecular identification from the liver revealed the DNA of H. capsulatum.
ISSN: 15730832
Appears in Collections:Scopus 2019

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