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Title: Anaphylaxis – Lessons learnt when East meets West
Authors: Elizabeth H. Tham
Agnes S.Y. Leung
Punchama Pacharn
Sooyoung Lee
Motohiro Ebisawa
Bee Wah Lee
Gary W.K. Wong
Ting Fan Leung
Sakura Sato
Lynette Pei Chi Shek
Kangmo Ahn
Pakit Vichyanond
Pantipa Chatchatee
Narissara Suratannon
National Sagamihara Hospital
National University Hospital, Singapore
Ajou University, School of Medicine
Yong Loo Lin School of Medicine
Prince of Wales Hospital Hong Kong
Faculty of Medicine, Siriraj Hospital, Mahidol University
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Nov-2019
Citation: Pediatric Allergy and Immunology. Vol.30, No.7 (2019), 681-688
Abstract: © 2019 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd. The rapidly increasing prevalence of allergic disorders over the past 2 decades highlights the need to understand the epidemiology of anaphylaxis. In Europe, the United States, and Australia, the incidence of anaphylaxis is estimated to be between 60 and 950 cases per 100 000 population, with a lifetime prevalence of anaphylaxis of 0.05%-2%. The incidence appears to be increasing over time. Although the existing Asian literature is heterogeneous and limited by under-reporting, it also suggests a similar increasing trend in anaphylaxis incidence in Asia. Anaphylaxis triggers in Asia, such as the predominance of shellfish and wheat in older children and adolescents, differ from those seen in Western populations. Triggers unique to Asia such as traditional Chinese medications, galacto-oligosaccharides, and food delicacies have also been reported. Low usage of adrenaline as first-line treatment of anaphylaxis is evident across all countries and is particularly concerning. There is a need to establish prospective, standardized protocols for anaphylaxis data collection and reporting, to enhance the collective understanding of anaphylaxis and its burden, gaps in management and to identify areas for future research and intervention in each region. Understanding of the underlying reasons explaining the difference between East and West will facilitate future primary preventive strategies.
ISSN: 13993038
Appears in Collections:Scopus 2019

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