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Title: Heart failure around the world
Authors: Jasper Tromp
João Pedro Ferreira
Satit Janwanishstaporn
Monica Shah
Barry Greenberg
Faiez Zannad
Carolyn S.P. Lam
UC San Diego Health
George Institute for Global Health
Université de Lorraine
Duke-NUS Medical School Singapore
Faculty of Medicine, Siriraj Hospital, Mahidol University
University of Groningen, University Medical Center Groningen
National Heart Centre, Singapore
Keywords: Medicine
Issue Date: 1-Oct-2019
Citation: European Journal of Heart Failure. Vol.21, No.10 (2019), 1187-1196
Abstract: © 2019 The Authors. European Journal of Heart Failure © 2019 European Society of Cardiology With increasingly large sample sizes required to demonstrate event reduction, heart failure outcome trials are no longer being performed in a small group of selected patients and countries, but at a global scale with worldwide contribution of patients from countries with considerable differences in background therapy, socioeconomic status and healthcare practices. Recent studies have highlighted how socioeconomic determinants rather than geographical factors may underlie the heterogeneity of patient populations across the globe. Therefore, in this review, we evaluated (i) regional differences in patient characteristics and outcomes in recent epidemiologic studies; (ii) regional differences in worldwide representativeness of clinical trial populations; and (iii) the role of socioeconomic determinants in driving country differences in heart failure trial enrolment and clinical outcomes.
ISSN: 18790844
Appears in Collections:Scopus 2019

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