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Authors: Ahmad M. Mansour
Robert E. Foster
Roberto Gallego-Pinazo
Marilita M. Moschos
Robert A. Sisk
Jay Chhablani
Duangnate Rojanaporn
Tharikarn Sujirakul
J. Fernando Arevalo
Luiz H. Lima
Lihteh Wu
Abdulrazzak Charbaji
Ali O. Saatci
Hana A. Mansour
Clara Martinez-Rubio
Yogin Patel
Sankeert Gangakhedkar
Rafik Hariri University Hospital
Université Libanaise
Lebanese American University
American University of Beirut
Hospital Universitari i Politècnic La Fe
Johns Hopkins Bayview Medical Center
National and Kapodistrian University of Athens
University of Cincinnati
L.V. Prasad Eye Institute India
Wilmer Eye Institute
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Universidade Federal de Sao Paulo
Dokuz Eylül Üniversitesi
Rutnin Eye Hospital
Coffee Research Institute of Costa Rica
Keywords: Medicine
Issue Date: 1-Jun-2019
Citation: Retina. Vol.39, No.6 (2019), 1133-1141
Abstract: © 2019 Ophthalmic Communications Society, Inc. Purpose:There is no established therapy for exudative-hemorrhagic complications in primary retinal arteriolar macroaneurysm (RAM).Methods:Retrospective multicenter interventional study of anti-vascular endothelial growth factor in symptomatic RAMs. Central macular thickness in m and best-corrected visual acuity in logMar were correlated with the RAM size and distance to the macula. Statistical analyses were performed using paired comparisons and Pearson correlation.Results:Thirty-two eyes (32 patients) were treated with a mean of 2.7 injections over a mean follow-up of 16.6 months. Initial best-corrected visual acuity correlated with the RAM size and distance to the macula (P = 0.02). Central macular thickness decreased by 131,180, and 211 m at 1, 2, and 3 months after the first injection (P < 0.001). Best-corrected visual acuity improved by 0.47 and 0.38 Early Treatment Diabetic Retinopathy Study lines at 2 and 3 months (P = 0.005). Anti-vascular endothelial growth factor response correlated with the RAM size (P = 0.04) and the distance to the macula (P = 0.009).Conclusion:Symptomatic RAMs can be treated successfully with anti-vascular endothelial growth factor injections, leading to a decrease in macular edema.
ISSN: 15392864
Appears in Collections:Scopus 2019

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