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dc.contributor.authorD. Songsaengen_US
dc.contributor.authorT. Sricharoenen_US
dc.contributor.authorB. Khiewvanen_US
dc.contributor.authorP. Pusuwanen_US
dc.contributor.authorS. Chuthapisithen_US
dc.contributor.authorS. Sriussadapornen_US
dc.contributor.authorT. Kunavisaruten_US
dc.contributor.authorW. Pongsapichen_US
dc.contributor.authorN. Chamsrien_US
dc.contributor.authorC. Boonmaen_US
dc.contributor.authorA. Suwanbunditen_US
dc.contributor.otherFaculty of Medicine, Siriraj Hospital, Mahidol Universityen_US
dc.contributor.otherSrinakharinwirot Universityen_US
dc.identifier.citationJournal of the Medical Association of Thailand. Vol.102, No.5 (2019), 576-581en_US
dc.description.abstract© JOURNAL OF THE MEDICAL ASSOCIATION OF THAILAND | 2019. Background: Four-dimensional computed tomography (4D-CT) improves the precision of pre-operative localization of hyperfunctioning parathyroid glands (HPGs). Objective: To analyze the role of pattern enhancement in 4D-CT imaging in hyperparathyroidism for differentiating HPGs from surrounding tissues for precision pre-operative localization of HPGs. Materials and Methods: The present retrospective study was conducted in patients who underwent 4D-CT scan of the parathyroid at the Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand between January 2013 and October 2016. Lesions were plotted for pattern enhancement, and mean Hounsfield units (HUs) of HPGs, lymph nodes, thyroid nodules, and thyroid glands were measured and analyzed. Results: Twenty-seven patients with 119 lesions were included. Significant difference was observed between both parathyroid adenoma and hyperplasia and thyroid gland during non-contrast phase and delayed 90-second phase. Attenuation value of less than 60 HUs in pre-contrast phase could differentiate HPGs from thyroid gland with 60% sensitivity and 85% specificity. Sensitivity of 4D-CT was 100% (95% Cl 73.5 to 100) for localization of all HPGs. Conclusion: Integration of clinical history data, conventional imaging, and 4D-CT imaging could improve differentiation of HPGs from surrounding tissues, thereby improving the precision of HPG localization during minimally invasive parathyroidectomy.en_US
dc.rightsMahidol Universityen_US
dc.titleFour-dimensional computed tomography pattern enhancement of parathyroid lesions in preoperative localization of hyperparathyroidismen_US
Appears in Collections:Scopus 2019

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