Simple jQuery Dropdowns
Please use this identifier to cite or link to this item:
Title: Morning surge in blood pressure and blood pressure variability in Asia: Evidence and statement from the HOPE Asia Network
Authors: Guru P. Sogunuru
Kazuomi Kario
Jinho Shin
Chen Huan Chen
Peera Buranakitjaroen
Yook C. Chia
Romeo Divinagracia
Jennifer Nailes
Sungha Park
Saulat Siddique
Jorge Sison
Arieska A. Soenarta
Jam C. Tay
Yuda Turana
Yuqing Zhang
Satoshi Hoshide
Ji Guang Wang
De La Salle Health Sciences Institute
Sunway University
Hanyang University Medical Center
Jichi Medical University
Shanghai Jiao Tong University School of Medicine
Madras Institute of Orthopaedics and Traumatology Hospitals
Kathmandu University
University of the East Ramon Magsaysay Memorial Medical Center
National Yang-Ming University Taiwan
Universitas Katolik Indonesia Atma Jaya
Universitas Indonesia
Fuwai Hospital
Faculty of Medicine, Siriraj Hospital, Mahidol University
Tan Tock Seng Hospital
Punjab Medical Center
Cardiovascular Hospital
Keywords: Medicine
Issue Date: 1-Feb-2019
Citation: Journal of Clinical Hypertension. Vol.21, No.2 (2019), 324-334
Abstract: ©2018 Wiley Periodicals, Inc. Hypertension is a major risk factor for cardiovascular and cerebrovascular diseases. To effectively prevent end-organ damage, maintain vascular integrity and reduce morbidity and mortality, it is essential to decrease and adequately control blood pressure (BP) throughout each 24-hour period. Exaggerated early morning BP surge (EMBS) is one component of BP variability (BPV), and has been associated with an increased risk of stroke and cardiovascular events, independently of 24-hour average BP. BPV includes circadian, short-term and long-term components, and can best be documented using out-of-office techniques such as ambulatory and/or home BP monitoring. There is a large body of evidence linking both BPV and EMBS with increased rates of adverse cardio- and cerebrovascular events, and end-organ damage. Differences in hypertension and related cardiovascular disease rates have been reported between Western and Asian populations, including a higher rate of stroke, higher prevalence of metabolic syndrome, greater salt sensitivity and more common high morning and nocturnal BP readings in Asians. This highlights a need for BP management strategies that take into account ethnic differences. In general, long-acting antihypertensives that control BP throughout the 24-hour period are preferred; amlodipine and telmisartan have been shown to control EMBS more effectively than valsartan. Home and ambulatory BP monitoring should form an essential part of hypertension management, with individualized pharmacotherapy to achieve optimal 24-hour BP control particularly the EMBS and provide the best cardio- and cerebrovascular protection. Future research should facilitate better understanding of BPV, allowing optimization of strategies for the detection and treatment of hypertension to reduce adverse outcomes.
ISSN: 17517176
Appears in Collections:Scopus 2019

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.