Please use this identifier to cite or link to this item:
|Title:||Celiac disease and risk of sarcoidosis: A systematic review and meta-analysis|
Juan E. Corral
Frank J. Lukens
Faculty of Medicine, Siriraj Hospital, Mahidol University
Mayo Clinic in Jacksonville, Florida
Chiang Mai University
Bassett Medical Center
|Citation:||Journal of Evidence-Based Medicine. Vol.12, No.3 (2019), 194-199|
|Abstract:||© 2019 Chinese Cochrane Center, West China Hospital of Sichuan University and John Wiley & Sons Australia, Ltd Background/objectives: Several epidemiologic studies have suggested that patients with celiac disease may be at an increased risk of sarcoidosis but the results were inconsistent. This systematic review and meta-analysis was conducted with the aim to better characterize this risk by summarizing all available data. Methods: A literature review was performed using MEDLINE and EMBASE database from inception to February 2019. Studies that compared the risk of sarcoidosis among patients with celiac disease versus individuals without celiac disease were included. Pooled odds ratio (OR) and 95% confidence interval (CI) were calculated using a random-effect, generic inverse variance method. Results: Of 426 retrieved studies, four studies with 693 639 participants met the eligibility criteria and were included in meta-analysis. The risk of sarcoidosis among patients with celiac disease was higher than individuals without celiac disease with the pooled OR of 7.16 (95% CI, 1.48-34.56). The statistical heterogeneity of this study was high (I2= 95%). Conclusions: This systematic review and meta-analysis found a significantly higher risk of sarcoidosis among patients with celiac disease.|
|Appears in Collections:||Scopus 2019|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.