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Title: Intestinal failure after bariatric surgery: Treatment and outcome at a single-intestinal rehabilitation and transplant center
Authors: Wethit Dumronggittigule
Elizabeth A. Marcus
Bernard J. DuBray
Robert S. Venick
Erik Dutson
Douglas G. Farmer
VA Greater Los Angeles Healthcare System
Mahidol University
David Geffen School of Medicine at UCLA
Keywords: Medicine
Issue Date: 1-Jan-2019
Citation: Surgery for Obesity and Related Diseases. Vol.15, No.1 (2019), 98-108
Abstract: © 2018 American Society for Bariatric Surgery Background: Though intestinal failure (IF) after bariatric surgery (BS) is uncommon, its prevalence is increasing. However, data on the outcomes for these patients are limited. Objectives: To analyze the outcomes of treatment for patients with IF after BS. Setting: University hospital. Methods: A single-center analysis (1991–2016) of outcomes according to treatment arms established by a multidisciplinary team. Results: Twenty-five IF patients were identified (median age 45 yr). BS was 92% Roux-en-Y gastric bypass. The major cause of IF was volvulus/internal hernia (72%). Median time from BS to IF was 48 months. Treatment arms were intestinal rehabilitation (IR, n = 15), transplantation (TXP, n = 5), and parenteral nutrition (PN, n = 5). For IR, median bowel length was 60 cm. Forty-six percent ultimately discontinued PN. Twenty-seven percent were partially weaned PN and 27% failed IR. Common surgical rehabilitation was Roux-en-Y gastric bypass reversal and restoration of gastrointestinal continuity. The 5-year overall survival was 74%. For TXP, 7 patients were listed for TXP (5 initially and 2 after failed IR). Three underwent TXP, 2 isolated intestine and 1 isolated liver. Three were delisted (1 improvement and 2 death). For PN, 6 patients required long-term PN (5 initially and 1 after failed IR). Four patients are alive currently. Conclusions: IF after BS is an increasing problem facing IR centers. Internal hernia is the major cause. Surgical IR is the first-line therapy and affords the best outcome. TXP is reserved for rescuing patients who failed IR or develop PN complications. Long-term PN is suitable for patients in whom IR or TXP is impractical.
ISSN: 18787533
Appears in Collections:Scopus 2019

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