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Title: Screening for phytochemicals and free radical scavenging activity of Vitex glabrata R.Br. fruit extract
Authors: Pornsak Laokijpaisal
Penchom Peungvicha
Nakkawee Saengklub
Supachoke Mangmool
Nutputsorn Chatsumpun
เพ็ญโฉม พึ่งวิชา
นรรฆวี แสงกลับ
ศุภโชค มั่งมูล
นัฏฐ์ภัสสร ชาติสัมปันน์
Mahidol University. Faculty of Pharmacy. Department of Physiology,
Mahidol University. Faculty of Pharmacy. Department of Pharmacology
Mahidol University. Faculty of Pharmacy. Department of Pharmacognosy
Keywords: Vitex glabrata (Vg);fruit;Phytochemicals;fruit extract
Issue Date: 2019
Abstract: Thai folk healers have claimed that ripe fruits of Vitex glabrata (Vg) are a remedy of malnutrition treatment usually associated with intestinal parasitism in children, diabetes, nephron tonic and erectile dysfunction. However, there is no scientific evidence support. The aim of this study is to investigate the phytochemical screening and free radical scavenging activity of the EtOH extract of Vg ripe fruits. The polyphenols, tannins, coumarins, triterpenes, and unsaturated lactone rings compounds were detected in EtOH Vg extract. The total phenolic content in the extract was 36.04±0.12 mg of GAE/g of dry plant material determined by Folin- Ciocalteu method. The DPPH assay showed that the extract had free radical scavenging activity, the IC50 was 346.64±4.48 μg/mL. The thin-layer chromatography (TLC) system was developed using chloroform: acetic acid (85:15) as a solvent system, the TLC chromatogram might be used as plant fingerprint in the future study.
Description: The 1st Pharmaceutical Sciences Asia Conference 2019 Theme : Pharmaceutical Sciences toward Health Innovation in the Disruptive Era. Bangkok Midtown Hotel, Thailand. August 22, 2019, page 64-69
Appears in Collections:PY-Proceeding Document

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