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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/54438
Title: Baseline chest computed tomography as standard of care in high‐risk hematology patients
Authors: Jannik Stemler
Caroline Bruns
Sibylle C. Mellinghoff
Nael Alakel
Hamdi Akan
Michelle Ananda‐rajah
Jutta Auberger
Peter Bojko
Pranatharthi H. Chandrasekar
Methee Chayakulkeeree
José A. Cozzi
Elizabeth A. de Kort
Andreas H. Groll
Christopher H. Heath
Larissa Henze
Marcos Hernandez Jimenez
Souha S. Kanj
Nina Khanna
Michael Koldehoff
Dong Gun Lee
Alina Mager
Francesco Marchesi
Rodrigo Martino‐bufarull
Marcio Nucci
Jarmo Oksi
Livio Pagano
Bob Phillips
Juergen Prattes
Athina Pyrpasopoulou
Werner Rabitsch
Enrico Schalk
Martin Schmidt‐hieber
Neeraj Sidharthan
Pere Soler‐palacín
Anat Stern
Barbora Weinbergerová
Aline El Zakhem
Oliver A. Cornely
Philipp Koehler
Fiona Stanley Hospital
PathWest Laboratory Medicine WA
Fondazione Policlinico Universitario Agostino Gemelli IRCCS Università Cattolica del Sacro Cuore
American University of Beirut Medical Center
Università Cattolica del Sacro Cuore, Rome
University of Western Australia
Universitätsspital Basel
Turun Yliopistollinen Keskussairaala
Dresden University Faculty of Medicine and University Hospital Carl Gustav Carus
Universität Rostock Uniklinikum und Medizinische Fakultät
Universidad de Carabobo
University of Cologne
Fakultni Nemocnice Brno
Wayne State University School of Medicine
Monash University
Otto von Guericke University of Magdeburg
University of York
IRCCS Regina Elena National Cancer Institute
Ankara Üniversitesi
Medizinische Universitat Wien
Faculty of Medicine, Siriraj Hospital, Mahidol University
Hospital de La Santa Creu I Sant Pau
Carl-Thiem-Klinikum
Uniklinik Köln
Amrita Institute of Medical Sciences India
Universitäts Klinikum Essen und Medizinische Fakultät
Leeds General Infirmary
Universitätsklinikum Münster
Medizinische Universität Graz
Hippokration General Hospital
The Catholic University of Korea
Radboud University Nijmegen Medical Centre
Universidade Federal do Rio de Janeiro
Onkologische Schwerpunktpraxis Freilassing
Pediatric Infectious Diseases and Immunodeficiencies Unit
German Center for Infection Research (DZIF), Partner Site Bonn-Cologne
Hospital Ciudad Dr. Enrique Tejera
Infectious Diseases Institute
Red Cross Hospital Munich
Hospital Provincial del Centenario
Keywords: Agricultural and Biological Sciences;Medicine
Issue Date: 1-Mar-2020
Citation: Journal of Fungi. Vol.6, No.1 (2020)
Abstract: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. Baseline chest computed tomography (BCT) in high‐risk hematology patients allows for the early diagnosis of invasive pulmonary aspergillosis (IPA). The distribution of BCT implementation in hematology departments and impact on outcome is unknown. A web‐based questionnaire was designed. International scientific bodies were invited. The estimated numbers of annually treated hematology patients, chest imaging timepoints and techniques, IPA rates, and follow‐up imaging were assessed. In total, 142 physicians from 43 countries participated. The specialties included infectious diseases (n = 69; 49%), hematology (n = 68; 48%), and others (n = 41; 29%). BCT was performed in 57% (n = 54) of 92 hospitals. Upon the diagnosis of malignancy or admission, 48% and 24% performed BCT, respectively, and X‐ray was performed in 48% and 69%, respectively. BCT was more often used in hematopoietic cell transplantation and in relapsed acute leukemia. European centers performed BCT in 59% and non‐European centers in 53%. Median estimated IPA rate was 8% and did not differ between BCT (9%; IQR 5–15%) and non‐BCT centers (7%; IQR 5–10%) (p = 0.69). Follow‐up computed tomography (CT) for IPA was performed in 98% (n = 90) of centers. In high‐risk hematology patients, baseline CT is becoming a standard‐of‐care. Chest X‐ray, while inferior, is still widely used. Randomized, controlled trials are needed to investigate the impact of BCT on patient outcome.
URI: http://repository.li.mahidol.ac.th/dspace/handle/123456789/54438
metadata.dc.identifier.url: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85082443992&origin=inward
ISSN: 2309608X
Appears in Collections:Scopus 2020

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