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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/54608
Title: Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: Post-hoc analysis of LAS VEGAS study
Authors: Chiara Robba
Sabrine N.T. Hemmes
Ary Serpa Neto
Thomas Bluth
Jaume Canet
Michael Hiesmayr
M. Wiersma Hollmann
Gary H. Mills
Marcos F. Vidal Melo
Christian Putensen
Samir Jaber
Werner Schmid
Paolo Severgnini
Hermann Wrigge
Denise Battaglini
Lorenzo Ball
Marcelo Gama De Abreu
Marcus J. Schultz
Paolo Pelosi
Wolfgang Kroell
Helfried Metzler
Gerd Struber
Thomas Wegscheider
Hans Gombotz
Michael Hiesmayr
Werner Schmid
Bernhard Urbanek
David Kahn
Mona Momeni
Audrey Pospiech
Fernande Lois
Patrice Forget
Irina Grosu
Jan Poelaert
Veerle Van Mossevelde
Marie Claire Van Malderen
Dimitri Dylst
Jeroen Van Melkebeek
Maud Beran
Stefan De Hert
Luc De Baerdemaeker
Bjorn Heyse
Jurgen Van Limmen
Piet Wyffels
Tom Jacobs
Nathalie Roels
Ann De Bruyne
Stijn Van De Velde
Brigitte Leva
Sandrine Damster
Benoit Plichon
Marina Juros-Zovko
Dejana Djonoviċ-Omanoviċ
Selma Pernar
Josip Zunic
Petar Miskovic
Antonio Zilic
Slavica Kvolik
Dubravka Ivic
Darija Azenic-Venzera
Sonja Skiljic
Hrvoje Vinkovic
Ivana Oputric
Kazimir Juricic
Vedran Frkovic
Jasminka Kopic
Ivan Mirkovic
Nenad Karanovic
Mladen Carev
Natasa Dropulic
Jadranka Pavicic Saric
Gorjana Erceg
Matea Bogdanovic Dvorscak
Branka Mazul-Sunko
Anna Marija Pavicic
Tanja Goranovic
Branka Maldini
Tomislav Radocaj
Zeljka Gavranovic
Inga Mladic-Batinica
Mirna Sehovic
Petr Stourac
Hana Harazim
Olga Smekalova
Martina Kosinova
Tomas Kolacek
Kamil Hudacek
Michal Drab
Jan Brujevic
Katerina Vitkova
Katerina Jirmanova
Ivana Volfova
Paula Dzurnakova
Katarina Liskova
Radovan Dudas
Radek Filipsky
Samir El Kafrawy
Hisham Hosny Abdelwahab
Tarek Metwally
Ahmed Abdel-Razek
Ospedale Policlinico San Martino
CHU Montpellier
Universitäts-Klinikum Bonn und Medizinische Fakultät
Massachusetts General Hospital
Dresden University Faculty of Medicine and University Hospital Carl Gustav Carus
Università degli Studi di Genova
Hospital Israelita Albert Einstein
Mahidol University
Hospital Universitari de Bellvitge
Medizinische Universitat Wien
Universität Leipzig
Università degli Studi dell'Insubria
University of Sheffield
Amsterdam UMC - University of Amsterdam
Keywords: Medicine
Issue Date: 2-Apr-2020
Citation: BMC Anesthesiology. Vol.20, No.1 (2020)
Abstract: © 2020 The Author(s). Background: Limited information is available regarding intraoperative ventilator settings and the incidence of postoperative pulmonary complications (PPCs) in patients undergoing neurosurgical procedures. The aim of this post-hoc analysis of the 'Multicentre Local ASsessment of VEntilatory management during General Anaesthesia for Surgery' (LAS VEGAS) study was to examine the ventilator settings of patients undergoing neurosurgical procedures, and to explore the association between perioperative variables and the development of PPCs in neurosurgical patients. Methods: Post-hoc analysis of LAS VEGAS study, restricted to patients undergoing neurosurgery. Patients were stratified into groups based on the type of surgery (brain and spine), the occurrence of PPCs and the assess respiratory risk in surgical patients in Catalonia (ARISCAT) score risk for PPCs. Results: Seven hundred eighty-four patients were included in the analysis; 408 patients (52%) underwent spine surgery and 376 patients (48%) brain surgery. Median tidal volume (VT) was 8 ml [Interquartile Range, IQR = 7.3-9] per predicted body weight; median positive end-expiratory pressure (PEEP) was 5 [3 to 5] cmH20. Planned recruitment manoeuvres were used in the 6.9% of patients. No differences in ventilator settings were found among the sub-groups. PPCs occurred in 81 patients (10.3%). Duration of anaesthesia (odds ratio, 1.295 [95% confidence interval 1.067 to 1.572]; p = 0.009) and higher age for the brain group (odds ratio, 0.000 [0.000 to 0.189]; p = 0.031), but not intraoperative ventilator settings were independently associated with development of PPCs. Conclusions: Neurosurgical patients are ventilated with low VT and low PEEP, while recruitment manoeuvres are seldom applied. Intraoperative ventilator settings are not associated with PPCs.
URI: http://repository.li.mahidol.ac.th/dspace/handle/123456789/54608
metadata.dc.identifier.url: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85082895096&origin=inward
ISSN: 14712253
Appears in Collections:Scopus 2020

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