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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/54624
Title: High blood pressure in dementia: How low can we go?
Authors: Yuda Turana
Jeslyn Tengkawan
Yook Chin Chia
Boon Wee Teo
Jinho Shin
Guru Prasad Sogunuru
Arieska Ann Soenarta
Huynh Van Minh
Peera Buranakitjaroen
Chen Huan Chen
Jennifer Nailes
Satoshi Hoshide
Sungha Park
Saulat Siddique
Jorge Sison
Apichard Sukonthasarn
Jam Chin Tay
Tzung Dau Wang
Narsingh Verma
Yu Qing Zhang
Ji Guang Wang
Kazuomi Kario
De La Salle Health Sciences Institute
Sunway University
National University Health System
Hanyang University Medical Center
Jichi Medical University
Yonsei University Health System
Shanghai Jiao Tong University School of Medicine
Madras Institute of Orthopaedics and Traumatology Hospitals
Kathmandu University
University of the East Ramon Magsaysay Memorial Medical Center
Hue University
Fatima Memorial Hospital
Universitas Katolik Indonesia Atma Jaya
Universitas Indonesia
University of Malaya
Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Yong Loo Lin School of Medicine
National Taiwan University College of Medicine
King George's Medical University
Faculty of Medicine, Siriraj Hospital, Mahidol University
National Yang-Ming University, School of Medicine
Tan Tock Seng Hospital
Chiang Mai University
Keywords: Medicine
Issue Date: 1-Mar-2020
Citation: Journal of Clinical Hypertension. Vol.22, No.3 (2020), 415-422
Abstract: © 2019 Wiley Periodicals, Inc. Hypertension is an important public health concern. The prevalence keeps increasing, and it is a risk factor for several adverse health outcomes including a decline in cognitive function. Recent data also show that the prevalence of hypertension and age-related dementia is rising in Asian countries, including in the oldest old group. This study aims to discuss possible treatments for high blood pressure in the elderly and propose an optimal target for BP relative to cognitive outcomes. This review discusses several studies on related blood pressure treatments that remain controversial and the consequences if the treatment target is too low or aggressive. Longitudinal, cross-sectional, and RCT studies were included in this review. An optimum systolic blood pressure of 120-130 mm Hg is recommended, especially in nondiabetic hypertensive patients with significant risk factors. In the oldest old group of patients, hypertension might have a protective effect. The use of calcium channel blockers (CCB) and angiotensin receptor blocker (ARB) is independently associated with a decreased risk of dementia in older people. However, personalized care for patients with hypertension, especially for patients who are frail or very old, is encouraged.
URI: http://repository.li.mahidol.ac.th/dspace/handle/123456789/54624
metadata.dc.identifier.url: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85076377016&origin=inward
ISSN: 17517176
15246175
Appears in Collections:Scopus 2020

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