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dc.contributor.authorYuda Turanaen_US
dc.contributor.authorJeslyn Tengkawanen_US
dc.contributor.authorYook Chin Chiaen_US
dc.contributor.authorBoon Wee Teoen_US
dc.contributor.authorJinho Shinen_US
dc.contributor.authorGuru Prasad Sogunuruen_US
dc.contributor.authorArieska Ann Soenartaen_US
dc.contributor.authorHuynh Van Minhen_US
dc.contributor.authorPeera Buranakitjaroenen_US
dc.contributor.authorChen Huan Chenen_US
dc.contributor.authorJennifer Nailesen_US
dc.contributor.authorSatoshi Hoshideen_US
dc.contributor.authorSungha Parken_US
dc.contributor.authorSaulat Siddiqueen_US
dc.contributor.authorJorge Sisonen_US
dc.contributor.authorApichard Sukonthasarnen_US
dc.contributor.authorJam Chin Tayen_US
dc.contributor.authorTzung Dau Wangen_US
dc.contributor.authorNarsingh Vermaen_US
dc.contributor.authorYu Qing Zhangen_US
dc.contributor.authorJi Guang Wangen_US
dc.contributor.authorKazuomi Karioen_US
dc.contributor.otherDe La Salle Health Sciences Instituteen_US
dc.contributor.otherSunway Universityen_US
dc.contributor.otherNational University Health Systemen_US
dc.contributor.otherHanyang University Medical Centeren_US
dc.contributor.otherJichi Medical Universityen_US
dc.contributor.otherYonsei University Health Systemen_US
dc.contributor.otherShanghai Jiao Tong University School of Medicineen_US
dc.contributor.otherMadras Institute of Orthopaedics and Traumatology Hospitalsen_US
dc.contributor.otherKathmandu Universityen_US
dc.contributor.otherUniversity of the East Ramon Magsaysay Memorial Medical Centeren_US
dc.contributor.otherHue Universityen_US
dc.contributor.otherFatima Memorial Hospitalen_US
dc.contributor.otherUniversitas Katolik Indonesia Atma Jayaen_US
dc.contributor.otherUniversitas Indonesiaen_US
dc.contributor.otherUniversity of Malayaen_US
dc.contributor.otherFuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical Collegeen_US
dc.contributor.otherYong Loo Lin School of Medicineen_US
dc.contributor.otherNational Taiwan University College of Medicineen_US
dc.contributor.otherKing George's Medical Universityen_US
dc.contributor.otherFaculty of Medicine, Siriraj Hospital, Mahidol Universityen_US
dc.contributor.otherNational Yang-Ming University, School of Medicineen_US
dc.contributor.otherTan Tock Seng Hospitalen_US
dc.contributor.otherChiang Mai Universityen_US
dc.identifier.citationJournal of Clinical Hypertension. Vol.22, No.3 (2020), 415-422en_US
dc.description.abstract© 2019 Wiley Periodicals, Inc. Hypertension is an important public health concern. The prevalence keeps increasing, and it is a risk factor for several adverse health outcomes including a decline in cognitive function. Recent data also show that the prevalence of hypertension and age-related dementia is rising in Asian countries, including in the oldest old group. This study aims to discuss possible treatments for high blood pressure in the elderly and propose an optimal target for BP relative to cognitive outcomes. This review discusses several studies on related blood pressure treatments that remain controversial and the consequences if the treatment target is too low or aggressive. Longitudinal, cross-sectional, and RCT studies were included in this review. An optimum systolic blood pressure of 120-130 mm Hg is recommended, especially in nondiabetic hypertensive patients with significant risk factors. In the oldest old group of patients, hypertension might have a protective effect. The use of calcium channel blockers (CCB) and angiotensin receptor blocker (ARB) is independently associated with a decreased risk of dementia in older people. However, personalized care for patients with hypertension, especially for patients who are frail or very old, is encouraged.en_US
dc.rightsMahidol Universityen_US
dc.titleHigh blood pressure in dementia: How low can we go?en_US
Appears in Collections:Scopus 2020

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