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Title: Comparison of day-to-day blood pressure variability in hypertensive patients with type 2 diabetes mellitus to those without diabetes: Asia BP@Home Study
Authors: Yook Chin Chia
Kazuomi Kario
Naoko Tomitani
Sungha Park
Jinho Shin
Yuda Turana
Jam Chin Tay
Peera Buranakitjaroen
Chen Huan Chen
Satoshi Hoshide
Jennifer Nailes
Huynh Van Minh
Saulat Siddique
Jorge Sison
Arieska Ann Soenarta
Guru Prasad Sogunuru
Apichard Sukonthasarn
Boon Wee Teo
Narsingh Verma
Yuqing Zhang
Tzung Dau Wang
Ji Guang Wang
University Medicine and Pharmacy, Hue University
De La Salle Health Sciences Institute
Sunway University
Hanyang University Medical Center
Jichi Medical University
Yonsei University Health System
Shanghai Jiao Tong University School of Medicine
Madras Institute of Orthopaedics and Traumatology Hospitals
National Taiwan University Hospital
Kathmandu University
University of the East Ramon Magsaysay Memorial Medical Center
Fatima Memorial Hospital
National Yang-Ming University Taiwan
Universitas Katolik Indonesia Atma Jaya
Universitas Indonesia
University of Malaya
Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Yong Loo Lin School of Medicine
King George's Medical University
Faculty of Medicine, Siriraj Hospital, Mahidol University
Tan Tock Seng Hospital
Bangkok Hospital Chiang Mai
Keywords: Medicine
Issue Date: 1-Mar-2020
Citation: Journal of Clinical Hypertension. Vol.22, No.3 (2020), 407-414
Abstract: © 2019 Wiley Periodicals, Inc. Blood pressure variability (BPV) has been shown to be independently associated with cardiovascular (CV) mortality and morbidity. Patients with type 2 diabetes mellitus (T2DM) have also been shown to have increased BPV. We aimed to compare BPV in hypertensive patients with diabetes with those without diabetes. A total of 1443 hypertensive patients measured their blood pressure (BP) twice in the morning and twice before bed at home for a week. Demographic data, history of T2DM, and anti-hypertensive use were captured. Clinic BP was measured twice in the clinic. Control of BP was defined as clinic systolic BP (SBP) <140 mm Hg and home SBP < 135 mm Hg. BPV was based on home SBP measurements. A total of 362(25.1%) hypertensives had diabetes and 47.4% were male. Mean age was 62.3 ± 12.1 years. There was no difference in the mean clinic SBP in both groups (139.9 mm Hg vs 138.4 mm Hg P =.188). However, the mean morning home SBP was significantly higher and control rate lower in hypertensives with diabetes than those without (132.3 ± 15 mm Hg vs 129.7 ± 14.4 mm Hg P =.005, 39.4% vs 47.6% P =.007), respectively. Masked uncontrolled morning hypertension was higher in those with diabetes versus those without (12.8% vs 8.4%, respectively). There was no statistically significant difference in BPV between those with and without diabetes. In summary, clinic SBP was similar in hypertensives with or without diabetes. However, control of BP based on both clinic and home SBP thresholds was poorer in hypertensives with diabetes compared to those without. Masked uncontrolled morning hypertension was higher in those with diabetes than those without. There was no difference in BPV between the two groups.
ISSN: 17517176
Appears in Collections:Scopus 2020

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