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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/57959
Title: Antimicrobial resistance surveillance in low-and middle-income countries: Progress and challenges in eight South Asian and Southeast Asian countries
Authors: Sumanth Gandra
Gerardo Alvarez-Uria
Paul Turner
Jyoti Joshi
Direk Limmathurotsakul
H. Rogier van Doorn
Oxford University Clinical Research Unit
Washington University School of Medicine in St. Louis
Mahidol University
Nuffield Department of Medicine
Rural Development Trust Hospital
Center for Disease Dynamics, Economics and Policy
Angkor Hospital for Children
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Jul-2020
Citation: Clinical Microbiology Reviews. Vol.33, No.3 (2020), 1-29
Abstract: © 2020 American Society for Microbiology. All Rights Reserved. Antimicrobial resistance (AMR) is a serious global health threat and is predicted to cause significant health and economic impacts, particularly in low-and middle-income countries (LMICs). AMR surveillance is critical in LMICs due to high burden of bacterial infections; however, conducting AMR surveillance in resource-limited settings is constrained by poorly functioning health systems, scarce financial resources, and lack of skilled personnel. In 2015, the United Nations World Health Assembly endorsed the World Health Organization’s Global Action Plan to tackle AMR; thus, several countries are striving to improve their AMR surveillance capacity, including making significant investments and establishing and expanding surveillance networks. Initial data generated from AMR surveillance networks in LMICs sug-gest the high prevalence of resistance, but these data exhibit several shortcomings, such as a lack of representativeness, lack of standardized laboratory practices, and underutilization of microbiology services. Despite significant progress, AMR surveillance networks in LMICs face several challenges in expansion and sustainability due to limited financial resources and technical capacity. This review summarizes the existing health infrastructure affecting the establishment of AMR surveillance pro-grams, the burden of bacterial infections demonstrating the need for AMR surveil-lance, and current progress and challenges in AMR surveillance efforts in eight South and Southeast Asian countries.
URI: http://repository.li.mahidol.ac.th/dspace/handle/123456789/57959
metadata.dc.identifier.url: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85086356648&origin=inward
ISSN: 10986618
08938512
Appears in Collections:Scopus 2020

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