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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/58230
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dc.contributor.authorApirada Thongsingen_US
dc.contributor.authorSurachai Likasitwattanakulaen_US
dc.contributor.authorTanaporn Netsuwanen_US
dc.contributor.authorOranee Sanmaneechaien_US
dc.contributor.otherFaculty of Medicine, Siriraj Hospital, Mahidol Universityen_US
dc.date.accessioned2020-08-25T11:07:44Z-
dc.date.available2020-08-25T11:07:44Z-
dc.date.issued2020-01-01en_US
dc.identifier.citationSiriraj Medical Journal. Vol.72, No.2 (2020), 125-131en_US
dc.identifier.issn22288082en_US
dc.identifier.other2-s2.0-85088647821en_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/58230-
dc.description.abstract© 2019 Faculty of Medicine Siriraj Hospital, Mahidol University. Objective: There are no epidemiological data on childhood neuromuscular diseases in Thailand. We aimed to estimate the proportion of NMDs among pediatric neurology patients in Siriraj Hospital and determine the specific diagnosis. Methods: A retrospective study was conducted in the pediatric neuromuscular clinic at Siriraj Hospital between 2014 and 2016. Results: Of 1,994 patients aged < 21 years with neurological diseases, 217 (10.88 %) had received a diagnosis. Diagnostic clarity can be achieved using clinical tools such as electromyography, serum creatinine kinase, muscle histo-immunology, and genetic analysis. Of the 217 patients, 143 (65.9 %) had inherited and 74 (34.1%) had acquired neuromuscular diseases. The most common inherited NMD were the Dystrophinopathies, including Duchenne / Becker muscular dystrophy (n = 58), while spinal muscular atrophy was the second most common (n = 25). Myasthenia Gravis was the most common acquired neuromuscular disease (n = 36). Conclusion: We found 10.88 percent of patients with neurological diseases have NMD. NMD is a chronic disease with poor quality of life and so multidisciplinary clinical care is crucial for these patients. In order to improve the standard of care, collaboration with government and other tertiary hospitals is important and will help serve a growing population of NMD patients.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85088647821&origin=inwarden_US
dc.subjectMedicineen_US
dc.titlePediatric neuromuscular diseases prevalence in Siriraj hospital, Thailand's largest tertiary referral hospitalen_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.33192/Smj.2020.17en_US
dc.identifier.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85088647821&origin=inwarden_US
Appears in Collections:Scopus 2020

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