Simple jQuery Dropdowns
Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/73721
Title: Cyclization of o-Alkynylisocyanobenzenes with 1,3-Dicarbonyl Compounds
Authors: Kannika La-Ongthong
Natthapat Sawekteeratana
Jasarin Klaysuk
Darunee Soorukram
Pawaret Leowanawat
Vichai Reutrakul
Sucheewin Krobthong
Patompon Wongtrakoongate
Chutima Kuhakarn
Mahidol University
Keywords: Chemistry
Issue Date: 1-Jan-2022
Citation: Synlett. (2022)
Abstract: A facile and convenient reaction of o-alkynylisocyanobenzenes with various active-methylene compounds, including 1,3-diesters, 1,3-diketones, β-keto esters, and β-keto amides, under Brønsted basic conditions, has been developed. Diethyl malonate reacted smoothly with a collection of o-alkynylisocyanobenzenes to provide the corresponding 2-quinolin-2-yl malonates in excellent yields. Acetylacetone gave a mixture of quinolin-4-yl and quinolin-2-yl derivatives. Acetoacetate esters and acetoacetyl amide derivative initially gave 2-quinolin-2-yl adducts that underwent partial deacetylation under the reaction conditions.
URI: http://repository.li.mahidol.ac.th/dspace/handle/123456789/73721
metadata.dc.identifier.url: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85127327728&origin=inward
ISSN: 14372096
09365214
Appears in Collections:Scopus 2022

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.