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dc.contributor.authorVermeersch, Audreyen_US
dc.contributor.authorLibaud-Moal, Anaëlleen_US
dc.contributor.authorRodrigues, Amabeliaen_US
dc.contributor.authorWhite, Nicholas Jen_US
dc.contributor.authorOlliaro, Pieroen_US
dc.contributor.authorGomes, Melbaen_US
dc.contributor.authorAshley, Elizabeth Aen_US
dc.contributor.authorMillet, Pascalen_US
dc.contributor.otherMahidol University. Faculty of Tropical Medicine.en_US
dc.date.accessioned2015-02-24T06:08:51Z
dc.date.accessioned2016-10-05T07:03:36Z-
dc.date.available2015-02-24T06:08:51Z
dc.date.available2016-10-05T07:03:36Z-
dc.date.copyright2014
dc.date.created2015-02-20
dc.date.issued2014-02-06
dc.identifier.citationVermeersch A, Libaud-Moal A, Rodrigues A, White NJ, Olliaro P, Gomes M, et al. Introducing the concept of a new pre-referral treatment for severely ill febrile children at community level: a sociological approach in Guinea-Bissau. Malar J. 2014 Feb 6;13:50.en_US
dc.identifier.issn1475-2875 (electronic)
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/768-
dc.description.abstractBACKGROUND: Innovative strategies are needed to tackle childhood mortality in the rural tropics. Artesunate suppositories were developed to bring emergency treatment closer to severely ill children with malaria in rural areas where injectable treatment is not possible for several hours. Adding an antibacterial rectal drug would extend this strategy to treat non-malarial febrile illness as well. The objective of these studies was to assess acceptability of such a new pre-referral strategy by healthcare providers and likely uptake by the population. METHODS: Two qualitative studies were conducted between May and July 2009. Study 1 investigated the acceptability of introducing a combined antimalarial-antibacterial suppository by interviewing 27 representatives of the three administrative levels (central government, regional, local) of the health sector; Study 2 investigated treatment-seeking behaviour and acceptability of this intervention at community level by interviewing 74 mothers in 2 villages. RESULTS AND CONCLUSIONS: Up to 92% of health representatives were in favour of introducing a new pre-referral strategy to tackle both malaria and non-malaria related severe illnesses in Guinea-Bissau, provided it was endorsed by international health authorities. The main obstacles to implementation were the very limited human and financial resources. In the two villages surveyed, 44% of the mothers associated severe illness with fever only, or fever plus one additional symptom. Mothers' judgement of severity and ensuing decisions were not specific for serious illness, indicating that initial training to recognize signs of severe disease and treatment availability for non-severe, fever-associated symptoms will be required to prevent overuse of a new intervention designed as a pre-referral treatment for severely ill children. Level C health centres were the first resort in both villages (50% and 87% of respondents respectively). This information is encouraging for the implementation of a pre-referral treatment.en_US
dc.language.isoenen_US
dc.rightsMahidol Universityen_US
dc.subjectAntibioticsen_US
dc.subjectArtesunateen_US
dc.subjectillnessesen_US
dc.subjectMalariaen_US
dc.subjectPre-referral treatmenten_US
dc.subjectRectal administrationen_US
dc.subjectRural areasen_US
dc.subjectSevere febrile illnessesen_US
dc.subjectOpen Access articleen_US
dc.titleIntroducing the concept of a new pre-referral treatment for severely ill febrile children at community level: a sociological approach in Guinea-Bissau.en_US
dc.typeArticleen_US
dc.rights.holderBioMed Centralen_US
dc.contributor.correspondenceMillet, Pascalen_US
dc.date.accepted2014-01-21
dc.identifier.doi10.1186/1475-2875-13-50.
dc.identifier.urlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922426/pdf/1475-2875-13-50.pdf
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