Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/9513
Title: Plant Antitumor Agents. 31. The Calycopterones, a New Class of Biflavonoids with Novel Cytotoxicity in a Diverse Panel of Human Tumor Cell Lines
Authors: Monroe E. Wall
Mansukh C. Wani
Fekadu Fullas
John B. Oswald
Dan M. Brown
Thawatchai Santisuk
Vichai Reutrakul
Andrew T. McPhail
Norman R. Farnsworth
John M. Pezzuto
A. Douglas Kinghorn
Jeffrey M. Besterman
RTI International
University of Illinois at Chicago
The Forest Herbarium, Thailand Ministry of Natural Resources and Environment
Mahidol University
P.M. Gross Chemical Laboratory
GlaxoSmithKline, USA
Royal Forest Herbarium
Duke University
Keywords: Biochemistry, Genetics and Molecular Biology;Pharmacology, Toxicology and Pharmaceutics
Issue Date: 1-May-1994
Citation: Journal of Medicinal Chemistry. Vol.37, No.10 (1994), 1465-1470
Abstract: Three new biflavonoids to which we have accorded the trivial names calycopterone (1), isocalycopterone (2), and 4-demethylcalycopterone (3) and the known flavone 4′,5-dihydroxy-3,3′,6,7-tetramethoxyflavone (4) were isolated as cytotoxic constituents from the flowers of Calycopteris floribunda Lamk. (Combretaceae). Compounds 1–3 showed a wide range of activity against a panel of solid tumor cell lines. Among the biflavonoids, calycopterone (1) is the major constituent. © 1994, American Chemical Society. All rights reserved.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0028318867&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/9513
ISSN: 15204804
00222623
Appears in Collections:Scopus 1991-2000

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