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Title: Ecdysteroids from vitex glabrata
Authors: Kittipong Werawattanametin
Verapong Podimuang
Apichart Suksamrarn
Mahidol University
Khon Kaen University
Ramkhamhaeng University
Keywords: Biochemistry, Genetics and Molecular Biology;Chemistry;Medicine;Pharmacology, Toxicology and Pharmaceutics
Issue Date: 1-Jan-1986
Citation: Journal of Natural Products. Vol.49, No.2 (1986), 365-366
Abstract: Vitex glabrata R. Br. (Verbenaceae) is a tree locally known as “Kai Nao” (1). The bark and root have reportedly been used as astringents. The bark has also been claimed to be an anthelmintic and a remedy for gastro-intestinal disorders (2,3). We report here the isolation and identification of two ecdysteroids: 20-hydroxyecdysone (4) and 1 la,20-dihydroxyecdysone (turkesterone) (5) from the bark of V. glabrata. Continuous liquid-liquid extraction provides a convenient and effective isolation of 20-hydroxyecdysone in high yield. The occurrences of 20-hydroxyecdysone and related ecdysteroids in Vitex megapotamica have been reported (6–8). To our knowledge, this is the first report of 11α,20-dihydroxyecdysone in Verbenaceae (9). © 1986, American Chemical Society. All rights reserved.
ISSN: 15206025
Appears in Collections:Scopus 1969-1990

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