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dc.contributor.authorPravan Suntharasamaien_US
dc.contributor.authorD. A. Warrellen_US
dc.contributor.authorSornchai Looareesuwanen_US
dc.contributor.authorM. J. Warrellen_US
dc.contributor.authorChaisin Viravanen_US
dc.contributor.authorWichai Supanaranonden_US
dc.contributor.authorPornthep Chanthavanichen_US
dc.contributor.authorAchara Supapochanaen_US
dc.contributor.authorWeera Tepsumethanonen_US
dc.contributor.authorX. Pouradier-Duteilen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherNuffield Department of Clinical Medicineen_US
dc.contributor.otherThai Red Cross Agencyen_US
dc.contributor.otherInstitut Merieuxen_US
dc.date.accessioned2018-02-27T04:28:59Z-
dc.date.available2018-02-27T04:28:59Z-
dc.date.issued1986-07-19en_US
dc.identifier.citationThe Lancet. Vol.328, No.8499 (1986), 129-131en_US
dc.identifier.issn01406736en_US
dc.identifier.other2-s2.0-0022655203en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0022655203&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/9807-
dc.description.abstractThe protective effect of a new, potentially economical tissue-culture rabies vaccine, purified vero-cell rabies vaccine (PVRV), was tested in 106 patients bitten by animals with proven rabies. 0·5 ml PVRV was given intramuscularly on days 0, 3, 7, 14, 28, and 91; 47 patients with severe exposure were also given 20 IU/kg human rabies immune globulin (HRIG). All patients are alive and well after 1 year. Side-effects of treatment were negligible. Rabies neutralising antibody (≥ 1·6 IU) was demonstrated on day 14 and persisted for 1 year in every case. There was no significant suppression of the antibody response by HRIG. If the untreated mortality is 15%, PVRV is 81% efficient in protecting patients against rabies encephalitis (95% confidence limit). PVRV is likely to replace human diploid-cell strain vaccine as the most widely used tissue-culture rabies vaccine. © 1986.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0022655203&origin=inwarden_US
dc.subjectMedicineen_US
dc.titleNEW PURIFIED VERO-CELL VACCINE PREVENTS RABIES IN PATIENTS BITTEN BY RABID ANIMALSen_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.1016/S0140-6736(86)91946-Xen_US
Appears in Collections:Scopus 1969-1990

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