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Title: Increased phagocytosis of Plasmodium falciparum-infected erythrocytes with haemoglobin E by peripheral blood monocytes
Authors: Ahnond Bunyaratvej
Punnee Butthep
Yongyuth Yuthavong
Suthat Fucharoen
Srisin Khusmith
Sutee Yoksan
Prawase Wasi
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Faculty of Science
Faculty of Medicine, Siriraj Hospital, Mahidol University
Mahidol University
Keywords: Medicine
Issue Date: 1-Jan-1986
Citation: Acta Haematologica. Vol.76, No.2-3 (1986), 155-158
Abstract: Erythrocytes from subjects with homozygous and heterozygous haemoglobin E (HbE) infected with Plasmodium falciparum in vitro were phagocytosed to a greater extent by normal human monocytes than infected erythrocytes from normal subjects. Susceptibility to phagocytosis was maximal when the parasites developed to trophozoite and schizont stages in both normal and patients' erythrocytes. The increased susceptibility of P. falciparum-infected HbE erythrocytes to phagocytosis by monocytes may play a role in protection against malaria. © 1986 S. Karger AG, Basel.
ISSN: 14219662
Appears in Collections:Scopus 1969-1990

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