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Title: | Increased phagocytosis of Plasmodium falciparum-infected erythrocytes with haemoglobin E by peripheral blood monocytes |
Authors: | Ahnond Bunyaratvej Punnee Butthep Yongyuth Yuthavong Suthat Fucharoen Srisin Khusmith Sutee Yoksan Prawase Wasi Faculty of Medicine, Ramathibodi Hospital, Mahidol University Faculty of Science Faculty of Medicine, Siriraj Hospital, Mahidol University Mahidol University |
Keywords: | Medicine |
Issue Date: | 1-Jan-1986 |
Citation: | Acta Haematologica. Vol.76, No.2-3 (1986), 155-158 |
Abstract: | Erythrocytes from subjects with homozygous and heterozygous haemoglobin E (HbE) infected with Plasmodium falciparum in vitro were phagocytosed to a greater extent by normal human monocytes than infected erythrocytes from normal subjects. Susceptibility to phagocytosis was maximal when the parasites developed to trophozoite and schizont stages in both normal and patients' erythrocytes. The increased susceptibility of P. falciparum-infected HbE erythrocytes to phagocytosis by monocytes may play a role in protection against malaria. © 1986 S. Karger AG, Basel. |
URI: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0022914687&origin=inward http://repository.li.mahidol.ac.th/dspace/handle/123456789/9854 |
ISSN: | 14219662 00015792 |
Appears in Collections: | Scopus 1969-1990 |
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