Browsing by Author "Loyola University Medical Center"

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    Corrigendum to ‘SJS/TEN 2019: From science to translation’ (Journal of Dermatological Science (2020) 98(1) (2–12), (S0923181120300645), (10.1016/j.jdermsci.2020.02.003))
    (2021-11-01) Wan Chun Chang; Riichiro Abe; Paul Anderson; Wanpen Anderson; Michael R. Ardern-Jones; Thomas M. Beachkofsky; Teresa Bellón; Agnieszka K. Biala; Charles Bouchard; Gianpiero L. Cavalleri; Nicole Chapman; James Chodosh; Hyon K. Choi; Ricardo R. Cibotti; Sherrie J. Divito; Karen Dewar; Ulrike Dehaeck; Mahyar Etminan; Diane Forbes; Esther Fuchs; Jennifer L. Goldman; James H. Holmes; Elyse A. Hope; Shuen Iu Hung; Chia Ling Hsieh; Alfonso Iovieno; Julienne Jagdeo; Mee Kum Kim; David M. Koelle; Mario E. Lacouture; Sophie Le Pallec; Rannakoe J. Lehloenya; Robyn Lim; Angie Lowe; Jean McCawley; Julie McCawley; Robert G. Micheletti; Maja Mockenhaupt; Katie Niemeyer; Michael A. Norcross; Douglas Oboh; Cristina Olteanu; Helena B. Pasieka; Jonathan Peter; Munir Pirmohamed; Michael Rieder; Hajirah N. Saeed; Neil H. Shear; Christine Shieh; Sabine Straus; Chonlaphat Sukasem; Cynthia Sung; Jason A. Trubiano; Sheng Ying Tsou; Mayumi Ueta; Simona Volpi; Chen Wan; Hongsheng Wang; Zhao Qing Wang; Jessica Weintraub; Cindy Whale; Lisa M. Wheatley; Sonia Whyte-Croasdaile; Kristina B. Williams; Galen Wright; Sonia N. Yeung; Li Zhou; Wen Hung Chung; Elizabeth J. Phillips; Bruce C. Carleton; Ramathibodi Hospital; Niigata University, Graduate School of Medical and Dental Science; Chinese Academy of Medical Sciences & Peking Union Medical College; European Medicines Agency; Instituto de Investigación Sanitaria del Hospital Universitario La Paz; Xiamen Chang Gung Hospital; Genome Canada; BC Children's Hospital Research Institute; Chang Gung University College of Medicine; National Yang-Ming University Taiwan; Chang Gung Memorial Hospital; Schulich School of Medicine & Dentistry; Wake Forest University School of Medicine; Health Sciences Authority, Government of Singapore; Vanderbilt University Medical Center; Kyoto Prefectural University of Medicine; Massachusetts General Hospital; Canadian Institutes of Health Research; University of Washington School of Medicine; Washington Hospital Center; University of Melbourne; Universität Freiburg; University of Southampton, Faculty of Medicine; University of British Columbia, Faculty of Medicine; Penn Medicine; University of Liverpool; Murdoch University; University of Alberta, Faculty of Medicine and Dentistry; Children's Mercy Hospitals and Clinics; Vanderbilt Eye Institute; Health Canada; Loyola University Medical Center; University of Toronto; University of Washington; Wilford Hall Ambulatory Surgical Center; The University of British Columbia; Food and Drug Administration; Memorial Sloan-Kettering Cancer Center; National Institutes of Health (NIH); National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS); Austin Health; Harvard Medical School; Seoul National University College of Medicine; University of Cape Town; Royal College of Surgeons in Ireland; SJS/TEN International Awareness (STIA); Association des malades des syndromes de Lyell et de Stevens-Johnson (Amalyste); SJ Syndrome of Texas; SJS Awareness Oregon; SJS Canada; Stevens-Johnson Syndrome Foundation; Eden Social Welfare Foundation; Genome British Columbia
    The authors regret not all contributing authors correctly acknowledged funding. Jonathan Peter's IMARI-Africa project (AFRISCAR) is part of the EDCTP2 programme supported by the European Union (grant number TMA2017SF-1981). The authors would like to apologise for any inconvenience caused.
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    The European Organization for Research and Treatment of Cancer quality of life questionnaire: Translation and reliability study of the Thai version
    (2002-11-01) Thitiya Sirisinha; Manmana Jirajarus; Chatchawan Silpakit; Tawee Tanvetyanon; Vorachai Ratanatharathorn; Suwanee Sirilerttrakul; Ekapop Sirachainan; Mahidol University; Loyola University Medical Center
    In the past decade, increasing attention is being given to more systematic and quantitative ways to evaluate explicitly the impact of disease and medical interventions on quality of life (QOL). Pertaining to the field of oncology, two relatively new instruments- the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 and the FACT-G, have received growing attention and appear to be excellent QOL instruments in clinical settings. FACT-G has already been validated and has been used in Thailand. Thus in the present study, the English version of the EORTC quality of life questionnaire (QLQ-C30) was translated into Thai and the initial descriptive statistic and scale reliability were reported. Mean score in this study of 75 cancer patients was comparable with the original report. Cronbach's alpha coefficient for multi-item scales range from 0.64 to 0.89. The validity of this translated version will be reported at a later date. The initial findings of the present study indicate that the Thai version of the EORTC QLQ-C30 is reliable. A validating process of this version is in progress with active patients accrual ongoing at present.
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    Mechanistic insights and characterization of sickle cell disease-associated cardiomyopathy
    (2014-01-01) Ankit A. Desai; Amit R. Patel; Homaa Ahmad; John V. Groth; Thejasvi Thiruvoipati; Kristen Turner; Chattanong Yodwut; Peter Czobor; Nicole Artz; Roberto F. MacHado; Joe G N Garcia; Roberto M. Lang; University of Illinois at Chicago; University of Chicago Medical Center; Ochsner Medical Center - New Orleans; Loyola University Medical Center; Mahidol University; Unity Point Health; University of Arizona
    Background-Cardiovascular disease is an important cause of morbidity and mortality in sickle cell disease (SCD). We sought to characterize sickle cell cardiomyopathy using multimodality noninvasive cardiovascular testing and identify potential causative mechanisms. Methods and Results-Stable adults with SCD (n=38) and healthy controls (n=13) prospectively underwent same day multiparametric cardiovascular magnetic resonance (cine, T2* iron, vasodilator frst pass myocardial perfusion, and late gadolinium enhancement imaging), transthoracic echocardiography, and applanation tonometry. Compared with controls, patients with SCD had severe dilation of the left ventricle (124±27 vs 79±12 mL/m2), right ventricle (127±28 vs 83±14 mL/m2), left atrium (65±16 vs 41±9 mL/m2), and right atrium (78±17 vs 56±17 mL/m 2; P<0.01 for all). Patients with SCD also had a 21% lower myocardial perfusion reserve index than control subjects (1.47±0.34 vs 1.87±0.37; P=0.034). A signifcant subset of patients with SCD (25%) had evidence of late gadolinium enhancement, whereas only 1 patient had evidence of myocardial iron overload. Diastolic dysfunction was present in 26% of patients with SCD compared with 8% in controls. Estimated flling pressures (E/e′, 9.3±2.7 vs 7.3±2.0; P=0.0288) were higher in patients with SCD. Left ventricular dilation and the presence of late gadolinium enhancement were inversely correlated to hepatic T2* times (ie, hepatic iron overload because of frequent blood transfusions; P<0.05 for both), whereas diastolic dysfunction and increased flling pressures were correlated to aortic stiffness (augmentation pressure and index, P<0.05 for all). Conclusions-Sickle cell cardiomyopathy is characterized by 4-chamber dilation and in some patients myocardial fbrosis, abnormal perfusion reserve, diastolic dysfunction, and only rarely myocardial iron overload. Left ventricular dilation and myocardial fbrosis are associated with increased blood transfusion requirements, whereas left ventricular diastolic dysfunction is predominantly correlated with increased aortic stiffness. © 2014 American Heart Association, Inc.
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    Mucoepidermoid carcinoma of the lung presenting as a cavitary lesion
    (2004-08-01) Tawee Tanvetyanon; Vorachai Ratanatharathorn; Juvady Leopairat; Loyola University Medical Center; Mahidol University
    The authors describe a 62-year-old female patient who presented with a progressively enlarging cavitary lesion in the right upper lobe of the lung. Acid-fast bacilli were recovered from a bronchial washing fluid and identified as Mycobacterium tuberculosis. She received antituberculous therapy for 5 months without improvement in her clinical symptoms and chest radiograph. A lobectomy was performed and pathological review demonstrated a high-grade mucoepidermoid lung carcinoma with extensive central necrosis. Staging revealed metastases in her left adrenal gland, kidney and spine. High-grade mucoepidermoid carcinoma of the lung may present as a cavitary lesion. The presence of M. tuberculosis should not preclude clinicians from pursuing adequate diagnostic procedures for a possible malignant lesion.
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    Non-Fellowship regional anesthesia training and assessment: An international Delphi study on a consensus curriculum
    (2021-10-01) Alwin Chuan; Bahaven Jeyaratnam; Shah Fathil; Leonardo H.C. Ferraro; Aneet Kessow; Yean Chin Lim; Michael J. O'Rourke; Vrushali Ponde; Julien Raft; Arthur Segurado; Suwimon Tangwiwat; Alexandra Torborg; Lloyd Turbitt; Andrew K. Lansdown; Edward R. Mariano; Colin J.L. McCartney; Alan J.R. MacFarlane; Louis Y.H. Mok; Steven L. Orebaugh; Amit Pawa; Santhanam Suresh; J. Balavenkat Subramanian; Thomas Volk; Glenn Woodworth; Reva Ramlogan; L'Hôpital d'Ottawa; Stanford University School of Medicine; Belfast Health and Social Care Trust; VA Palo Alto Health Care System; Prince of Wales Hospital Hong Kong; Universitätsklinikum des Saarlandes Medizinische Fakultät der Universität des Saarlandes; Royal Prince Alfred Hospital; Glasgow Royal Infirmary; Loyola University Medical Center; Oregon Health & Science University; Universidade Federal de São Paulo; VA Medical Center; Changi General Hospital; Mahidol University; University of Pittsburgh Medical Center; UNSW Medicine; University of KwaZulu-Natal; Northwestern University; Hospital Sirio-Libanês; St Thomas' Hospital; University of Cape Town; Hinduja Health Care Surgical and Research Centre; Gleneagles Hospital Medini Johor; Institut de Cancérologie de Lorraine; Ganga Medical Centre and Hospitals Pvt Ltd
    Background and objectives While there are several published recommendations and guidelines for trainees undertaking subspecialty Fellowships in regional anesthesia, a similar document describing a core regional anesthesia curriculum for non-fellowship trainees is less well defined. We aimed to produce an international consensus for the training and teaching of regional anesthesia that is applicable for the majority of worldwide anesthesiologists. Methods This anonymous, electronic Delphi study was conducted over two rounds and distributed to current and immediate past (within 5 years) directors of regional anesthesia training worldwide. The steering committee formulated an initial list of items covering nerve block techniques, learning objectives and skills assessment and volume of practice, relevant to a non-fellowship regional anesthesia curriculum. Participants scored these items in order of importance using a 10-point Likert scale, with free-text feedback. Strong consensus items were defined as highest importance (score ≥8) by ≥70% of all participants. Results 469 participants/586 invitations (80.0% response) scored in round 1, and 402/469 participants (85.7% response) scored in round 2. Participants represented 66 countries. Strong consensus was reached for 8 core peripheral and neuraxial blocks and 17 items describing learning objectives and skills assessment. Volume of practice for peripheral blocks was uniformly 16-20 blocks per anatomical region, while ≥50 neuraxial blocks were considered minimum. Conclusions This international consensus study provides specific information for designing a non-fellowship regional anesthesia curriculum. Implementation of a standardized curriculum has benefits for patient care through improving quality of training and quality of nerve blocks.
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    SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation
    (2018-01-01) Katie D. White; Riichiro Abe; Michael Ardern-Jones; Thomas Beachkofsky; Charles Bouchard; Bruce Carleton; James Chodosh; Ricardo Cibotti; Robert Davis; Joshua C. Denny; Roni P. Dodiuk-Gad; Elizabeth N. Ergen; Jennifer L. Goldman; James H. Holmes; Shuen Iu Hung; Mario E. Lacouture; Rannakoe J. Lehloenya; Simon Mallal; Teri A. Manolio; Robert G. Micheletti; Caroline M. Mitchell; Maja Mockenhaupt; David A. Ostrov; Rebecca Pavlos; Munir Pirmohamed; Elena Pope; Alec Redwood; Misha Rosenbach; Michael D. Rosenblum; Jean Claude Roujeau; Arturo P. Saavedra; Hajirah N. Saeed; Jeffery P. Struewing; Hirohiko Sueki; Chonlaphat Sukasem; Cynthia Sung; Jason A. Trubiano; Jessica Weintraub; Lisa M. Wheatley; Kristina B. Williams; Brandon Worley; Wen Hung Chung; Neil H. Shear; Elizabeth J. Phillips; Duke-NUS Medical School Singapore; National Yang-Ming University Taiwan; Chang Gung Memorial Hospital; Wake Forest University School of Medicine; Health Sciences Authority, Government of Singapore; Vanderbilt University Medical Center; Hospital for Sick Children University of Toronto; Massachusetts General Hospital; University of Ottawa, Canada; Showa University School of Medicine; Niigata University School of Medicine; The University of Alabama at Birmingham; University of Melbourne; Wake Forest University Baptist Medical Center; Universität Freiburg im Breisgau; University of Southampton; Universite Paris 12 Val de Marne; University of California, San Francisco; Technion - Israel Institute of Technology; University of Liverpool; Murdoch University; Children's Mercy Hospitals and Clinics; National Institute of Allergy and Infectious Diseases; Loyola University Medical Center; University of Toronto; Faculty of Medicine, Ramathibodi Hospital, Mahidol University; University of Florida; National Human Genome Research Institute; The University of British Columbia; Food and Drug Administration; Memorial Sloan-Kettering Cancer Center; BC Children's Hospital; Uniformed Services University of the Health Sciences; University of Pennsylvania; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Austin Health; Groote Schuur Hospital; Harvard Medical School; University of Tennessee Health Science Center; Lackland Air Force Base
    © 2017 American Academy of Allergy, Asthma & Immunology Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a life-threatening, immunologically mediated, and usually drug-induced disease with a high burden to individuals, their families, and society with an annual incidence of 1 to 5 per 1,000,000. To effect significant reduction in short- and long-term morbidity and mortality, and advance clinical care and research, coordination of multiple medical, surgical, behavioral, and basic scientific disciplines is required. On March 2, 2017, an investigator-driven meeting was held immediately before the American Academy of Dermatology Annual meeting for the central purpose of assembling, for the first time in the United States, clinicians and scientists from multiple disciplines involved in SJS/TEN clinical care and basic science research. As a product of this meeting, this article summarizes the current state of knowledge and expert opinion related to SJS/TEN covering a broad spectrum of topics including epidemiology and pharmacogenomic networks; clinical management and complications; special populations such as pediatrics, the elderly, and pregnant women; regulatory issues and the electronic health record; new agents that cause SJS/TEN; pharmacogenomics and immunopathogenesis; and the patient perspective. Goals include the maintenance of a durable and productive multidisciplinary network that will significantly further scientific progress and translation into prevention, early diagnosis, and management of SJS/TEN.
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    SJS/TEN 2019: From science to translation
    (2020-01-01) Wan Chun Chang; Riichiro Abe; Paul Anderson; Wanpen Anderson; Michael R. Ardern-Jones; Thomas M. Beachkofsky; Teresa Bellón; Agnieszka K. Biala; Charles Bouchard; Gianpiero L. Cavalleri; Nicole Chapman; James Chodosh; Hyon K. Choi; Ricardo R. Cibotti; Sherrie J. Divito; Karen Dewar; Ulrike Dehaeck; Mahyar Etminan; Diane Forbes; Esther Fuchs; Jennifer L. Goldman; James H. Holmes; Elyse A. Hope; Shuen Iu Hung; Chia Ling Hsieh; Alfonso Iovieno; Julienne Jagdeo; Mee Kum Kim; David M. Koelle; Mario E. Lacouture; Sophie Le Pallec; Rannakoe J. Lehloenya; Robyn Lim; Angie Lowe; Jean McCawley; Julie McCawley; Robert G. Micheletti; Maja Mockenhaupt; Katie Niemeyer; Michael A. Norcross; Douglas Oboh; Cristina Olteanu; Helena B. Pasieka; Jonathan Peter; Munir Pirmohamed; Michael Rieder; Hajirah N. Saeed; Neil H. Shear; Christine Shieh; Sabine Straus; Chonlaphat Sukasem; Cynthia Sung; Jason A. Trubiano; Sheng Ying Tsou; Mayumi Ueta; Simona Volpi; Chen Wan; Hongsheng Wang; Zhao Qing Wang; Jessica Weintraub; Cindy Whale; Lisa M. Wheatley; Sonia Whyte-Croasdaile; Kristina B. Williams; Galen Wright; Sonia N. Yeung; Li Zhou; Wen Hung Chung; Elizabeth J. Phillips; Bruce C. Carleton; Chinese Academy of Medical Sciences & Peking Union Medical College; European Medicines Agency; Instituto de Investigación Hospital Universitario La Paz (IdiPAZ); Xiamen Chang Gung Hospital; Genome Canada; National Yang-Ming University Taiwan; Chang Gung Memorial Hospital; Wake Forest School of Medicine; Health Sciences Authority, Government of Singapore; University of Alberta; Vanderbilt University Medical Center; Kyoto Prefectural University of Medicine; Massachusetts General Hospital; Canadian Institutes of Health Research; Niigata University School of Medicine; Washington Hospital Center; University of Melbourne; Universität Freiburg im Breisgau; University of Southampton, Faculty of Medicine; University of Liverpool; Chang Gung University; Murdoch University; Children's Mercy Hospitals and Clinics; Vanderbilt Eye Institute; Health Canada; National Institute of Allergy and Infectious Diseases; Loyola University Medical Center; University of Toronto; Faculty of Medicine, Ramathibodi Hospital, Mahidol University; University of Washington, Seattle; National Human Genome Research Institute; Western University; The University of British Columbia; Food and Drug Administration; Memorial Sloan-Kettering Cancer Center; BC​ Children​'​​s Hospital; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Austin Health; University of Pennsylvania Perelman School of Medicine; Harvard Medical School; Lackland Air Force Base; Seoul National University College of Medicine; University of Cape Town; Royal College of Surgeons in Ireland (RCSI); SJS/TEN International Awareness (STIA); Association des malades des syndromes de Lyell et de Stevens-Johnson (Amalyste); SJ Syndrome of Texas; SJS Awareness Oregon; SJS Canada; Stevens-Johnson Syndrome Foundation; Eden Social Welfare Foundation; Genome British Columbia
    © 2020 Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are potentially life-threatening, immune-mediated adverse reactions characterized by widespread erythema, epidermal necrosis, and detachment of skin and mucosa. Efforts to grow and develop functional international collaborations and a multidisciplinary interactive network focusing on SJS/TEN as an uncommon but high burden disease will be necessary to improve efforts in prevention, early diagnosis and improved acute and long-term management. SJS/TEN 2019: From Science to Translation was a 1.5-day scientific program held April 26–27, 2019, in Vancouver, Canada. The meeting successfully engaged clinicians, researchers, and patients and conducted many productive discussions on research and patient care needs.
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    Targeted expression of the E6 and E7 oncogenes of human papillomavirus type 16 in the epidermis of transgenic mice elicits generalized epidermal hyperplasia involving autocrine factors
    (1994-01-01) Prasert Auewarakul; Lutz Gissmann; Angel Cid-Arregui; German Cancer Research Center; European Molecular Biology Laboratory Heidelberg; Mahidol University; Loyola University Medical Center
    The E6 and E7 early genes of human papillomavirus type 16 have been shown in vitro to play a central role in the transforming capability of this virus. To explore their effects on differentiating epithelial cells in vivo, we used a bovine cytokeratin 10 (K10) promoter to target the expression of E6 and E7 to the suprabasal layers of the epidermis of transgenic mice. In two different lines of mice efficiently expressing the transgene, animals displayed generalized epidermal hyperplasia, hyperkeratosis and parakeratosis in the skin and the forestomach, both known to be sites of K10 expression. Northern (RNA) blot analysis revealed high levels of E6 and E7 transcripts, and in situ hybridizations localized these transcripts to the suprabasal strata of epidermis. In vivo labeling of proliferating cells showed two distinct effects of E6 and E7 expression in the epidermis: (i) an increase in the number of growing cells in the undifferentiated basal layer and (ii) abnormal proliferation of differentiated cells in the suprabasal strata. The expression of c-myc in the skin of transgenics was higher than that in control animals. The induction of c-myc transcription by topical application of tetradecanoyl phorbol acetate was prevented by simultaneous treatment with transforming growth factor β1 in nontransgenic skin but not in transgenic skin. In addition, transforming growth factor α was found to be overexpressed in the suprabasal layers of the transgenic epidermis. These findings suggest that autocrine mechanisms are involved in the development and maintenance of epidermal hyperplasia. Animals of both lines developed papillomas in skin sites exposed to mechanical irritation and wounding, suggesting that secondary events are necessary for progression to neoplasia. Collectively, these results provide new insights into the tumor promoter activities of human papillomavirus type 16 in epithelial cells in vivo.
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    Tracheostomy During the COVID-19 Pandemic: Comparison of International Perioperative Care Protocols and Practices in 26 Countries
    (2021-06-01) Carol Bier-Laning; John D. Cramer; Soham Roy; Patrick A. Palmieri; Ayman Amin; José Manuel Añon; Cesar A. Bonilla-Asalde; Patrick J. Bradley; Pankaj Chaturvedi; David M. Cognetti; Fernando Dias; Arianna Di Stadio; Johannes J. Fagan; David J. Feller-Kopman; Sheng Po Hao; Kwang Hyun Kim; Petri Koivunen; Woei Shyang Loh; Jobran Mansour; Matthew R. Naunheim; Marcus J. Schultz; You Shang; Davud B. Sirjani; Maie A. St. John; Joshua K. Tay; Sébastien Vergez; Heather M. Weinreich; Eddy W.Y. Wong; Johannes Zenk; Christopher H. Rassekh; Michael J. Brenner; School of Medicine; Hospital Nacional Daniel Alcides Carrión; Universidad Privada San Juan Bautista; Universidad Norbert Wiener; University of Michigan Medical School; Stanford University School of Medicine; Pontifícia Universidade Católica do Rio de Janeiro; NUS Yong Loo Lin School of Medicine; University of Illinois College of Medicine; University of Texas Medical School at Houston; Shin-Kong Wu Ho-Su Memorial Hospital Taiwan; Wayne State University School of Medicine; Tata Memorial Hospital; Loyola University Medical Center; National University of Singapore; Oulu University Hospital; Thomas Jefferson University; University of Nottingham; Mahidol University; Chaim Sheba Medical Center Israel; Cairo University; Nuffield Department of Medicine; Hôpital Rangueil; University of Pennsylvania; David Geffen School of Medicine at UCLA; Massachusetts Eye and Ear Infirmary; Università degli Studi di Perugia; Chinese University of Hong Kong; Universidad Carlos III de Madrid; Tongji Medical College; Amsterdam UMC - University of Amsterdam; Johns Hopkins School of Medicine; Seoul National University College of Medicine; University of Cape Town; Evidence-Based Health Care South America: A Joanna Briggs Institute Affiliated Group; Global Tracheostomy Collaborative; Universitätsklinikum Augsburg Klinik für HNO-Heilkunde
    Objective: The coronavirus disease 2019 (COVID-19) pandemic has led to a global surge in critically ill patients requiring invasive mechanical ventilation, some of whom may benefit from tracheostomy. Decisions on if, when, and how to perform tracheostomy in patients with COVID-19 have major implications for patients, clinicians, and hospitals. We investigated the tracheostomy protocols and practices that institutions around the world have put into place in response to the COVID-19 pandemic. Data Sources: Protocols for tracheostomy in patients with severe acute respiratory syndrome coronavirus 2 infection from individual institutions (n = 59) were obtained from the United States and 25 other countries, including data from several low- and middle-income countries, 23 published or society-endorsed protocols, and 36 institutional protocols. Review Methods: The comparative document analysis involved cross-sectional review of institutional protocols and practices. Data sources were analyzed for timing of tracheostomy, contraindications, preoperative testing, personal protective equipment (PPE), surgical technique, and postoperative management. Conclusions: Timing of tracheostomy varied from 3 to >21 days, with over 90% of protocols recommending 14 days of intubation prior to tracheostomy. Most protocols advocate delaying tracheostomy until COVID-19 testing was negative. All protocols involved use of N95 or higher PPE. Both open and percutaneous techniques were reported. Timing of tracheostomy changes ranged from 5 to >30 days postoperatively, sometimes contingent on negative COVID-19 test results. Implications for Practice: Wide variation exists in tracheostomy protocols, reflecting geographical variation, different resource constraints, and limited data to drive evidence-based care standards. Findings presented herein may provide reference points and a framework for evolving care standards.
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    Workshop on research priorities for management and treatment of angiostrongyliasis
    (2012-12-01) Robert H. Cowie; James R. Hollyer; Alexandre J. da Silva; Robert G. Hollingsworth; Marlena C. Dixon; Praphathip Eamsobhana; Le Anne M. Fox; William L. Gosnell; Kathleen Howe; Stuart Johnson; Jaynee R. Kim; Kenton J. Kramer; Phaik Eem Lim; John F. Lindo; Zhao Rong Lun; Arnaldo Maldonado; Alessandra L. Morassutti; Gerald S. Murphy; Sarah Y. Park; Yvonne Qvarnstrom; Ralph D. Robinson; Kittisak Sawanyawisuth; John Teem; Silvana C. Thiengo; Cheridah D. Todd; Hung Chin Tsai; Gordon D. Wallace; Cecelia A. Waugh; A. Christian Whelen; Patricia P. Wilkins; Ting Bao Yang; Hoi Sen Yong; University of Hawaii at Manoa; Centers for Disease Control and Prevention; Hawaii Department of Health; John A. Burns School of Medicine; Mahidol University; United States Department of Agriculture; Loyola University Medical Center; University of Malaya; Sun Yat-Sen University; Fundacao Oswaldo Cruz; Pontificia Universidade Catolica do Rio Grande do Sul; U.S. Army Pacific Regional Medical Command - Tripler Army Medical Center; University of the West Indies; Khon Kaen University; Florida Department of Agriculture & Consumer services; National Yang-Ming University Taiwan