Publication: Dermal Pathology in Melasma: An Update Review
Submitted Date
Received Date
Accepted Date
Issued Date
2022-01-01
Copyright Date
Announcement No.
Application No.
Patent No.
Valid Date
Resource Type
Edition
Resource Version
Language
File Type
No. of Pages/File Size
ISBN
ISSN
11787015
eISSN
Scopus ID
WOS ID
Pubmed ID
arXiv ID
Call No.
Other identifier(s)
2-s2.0-85123862105
Journal Title
Volume
Issue
item.page.oaire.edition
Start Page
End Page
Access Rights
Access Status
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Physical Location
Bibliographic Citation
Clinical, Cosmetic and Investigational Dermatology. Vol.15, (2022), 11-19
Citation
Kachanat Phansuk, Vasanop Vachiramon, Natthachat Jurairattanaporn, Kumutnart Chanprapaph, Teerapong Rattananukrom (2022). Dermal Pathology in Melasma: An Update Review. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/75096.
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Dermal Pathology in Melasma: An Update Review
Alternative Title(s)
Author's Affiliation
Author's E-mail
Editor(s)
Editor's Affiliation
Corresponding Author(s)
Creator(s)
Compiler
Advisor(s)
Illustrator(s)
Applicant(s)
Inventor(s)
Issuer
Assignee
Other Contributor(s)
Series
Has Part
Abstract
Background: Melasma is a complex and multipathophysiological condition that is challenging to treat. The roles of each element in the dermis were highlighted in this recent year due to targeting it with emerging therapies. Although some studies have demonstrated abnormal findings in the dermis of melasma lesions, there are no integrated data regarding these findings. Purpose: This article aims to discuss each finding in the dermis of melasma lesions and to provide some ideas about treatment options. Methods: An Internet search was completed using the MEDLINE, Embase, Scopus, and Google Scholar databases for relevant literature through June 2021 and reference lists of respective articles. Only the articles published in English language were included. Results: Several studies have focused on the dermal changes in melasma. Common findings included basement membrane disruption, pendulous melanocytes, marked solar elastosis, increased melanophages, increased mast cells, and neovascularization. In addition, each of them had the specified mechanism that may relate with the others. Conclusion: Several changes in the dermis of melasma lesion may be connected with pathological changes in the epidermis. This may serve as a potential target treatment for melasma, which requires a multimodal approach.