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Publication Open Access ผลของโปรแกรมสนับสนุนและการให้ความรู้ต่อความรู้และพฤติกรรมการควบคุมปริมาณน้ำของผู้ดูแล และน้ำหนักที่เพิ่มขึ้นของผู้ที่ได้รับการฟอกเลือดด้วยเครื่องไตเทียม(2568) เยาวลักษณ์ จันทรเรืองนภา; นพวรรณ พินิจขจรเดช; สุชิรา ชัยวิบูลย์ธรรม; Yaowalak Chandraruangnabha; Noppawan Phinitkhajorndech; Suchira Chaiviboonthammust be placed on fluid volume management protocols to prevent volume overload. This quasi-experimental study investigates the effects of an educational support program on caregivers’ knowledge and behaviors regarding volume control for patients... program. Data were collected from April to July 2021. The supportive education program consisted of three phases: self-awareness and knowledge promotion, skill training, and continuous care for four weeks. A follow-up evaluation was conducted for anotherPublication Open Access ผลของโปรแกรมกำกับตนเองเพื่อควบคุมภาวะน้ำเกินในผู้ป่วยไตวายเรื้อรัง ระยะสุดท้ายที่ได้รับการบำบัดทดแทนไตด้วยวิธีการล้างไตทางช่องท้องอย่างต่อเนื่อง(2560) กชกร คำเรือง; ศรัณญา เบญจกุล; ธราดล เก่งการพานิช; มณฑา เก่งการพานิช; กรกนก ลัธธนันท์; Kotchakorn Kumruang; Sarunya Benjakul; Tharadol Kengganpanich; Mondha Kengganpanich; Kornkanok Lattanand; มหาวิทยาลัยมหิดล. คณะสาธารณสุขศาสตร์. ภาควิชาสุขศึกษาและพฤติกรรมศาสตร์This quasi-experimental research aimed to study the effects of a self-regulated program to control volume overload among patients with end stage renal disease receiving continuous ambulatory peritoneal dialysis. A sample of 44 patients... and supported self-observation continuously, to control volume overload. Data were collected pre- and post intervention by interviewing and measuring volume overload at weeks 1, 5 and 9. Data was analyzed using descriptive and inferential statisticsPublication Open Access Identification and key management of non-transfusion-dependent thalassaemia patients: not a rare but potentially under-recognised condition(2014) Vip Viprakasit; Tyan, Paul; Sarayuth Rodmai; Taher, Ali T.; Mahidol University. Faculty of Medicine, Siriraj Hospital. Department of Pediatrics and Thalassemia Centerspleen and/or liver, skeletal deformities, growth retardation, elevated serum ferritin and iron overload. The contributing factors to disease progression are ineffective erythropoiesis and increased haemolysis, which lead to chronic anaemia. The body’sPublication Open Access Glutathione Redox system in Beta-Thalassemia/Hb E patients(2013) Kalpravidh, Ruchaneekorn W.; Thongchai Tangjaidee; Suneerat Hatairaktham; Ratiya Charoensakdi; Narumol Panichkul; Noppadol Siritanaratkul; Suthat Fucharoen; Mahidol University. Institute of Molecular Biosciences. Thalassemia Research Center; Mahidol University. Faculty of Medicine Siriraj Hospital. Department of Medicine; Mahidol University. Faculty of Medicine Siriraj Hospital. Department of Biochemistryβ-thalassemia/Hb E is known to cause oxidative stress induced by iron overload. The glutathione system is the major endogenous antioxidant that protects animal cells from oxidative damage. This study aimed to determine the effect of disease stateItem Open Access A study of cyber range functions in cybersecurity risk management by using the NIST framework(Mahidol University, 2023) Rujirekh Saetiea; Rojjalak Chuckpaiwong; Sotarat ThammaboosadeeTechnology has played a role in almost every organization, regardless of size, as an addition to some organizations, or as the core of some organizations, in response to the expanding business competition in the Internet world. Though technology develops rapidly, threats and attacks go beyond; organizations must adapt and prepare their resources, not only the technology used for protection but also the readiness and understanding of the risks from threats and attacks from employees throughout the organization. The purpose of this study was to research the capabilities of the Cyber Range platform where to help mitigate global cyber threats and the concept to perform cybersecurity risk assessment according to the National Institute of Standards and Technology (NIST) Cybersecurity Framework and special publication related to the risk management such as SP800-30 and SP800-39. This study selected the threat events for cyber-attacks are characterized by the tactics, techniques, and procedures (TTPs) employed by adversaries; after that, to conduct the cybersecurity risk assessment to come up with the potential impact, and the final step was mapping feature of Cyber Range to mitigate the risk. It was found risk level of the potential impact based on the cyber threat selected and guidance mapped Cyber Range to the organization that would like to start their risk management strategy. Implication of the thematic paper: The results provide suggestions and recommendations on how to start implement the risk management of organization in general using NIST framework and Cyber Range functions.Publication Open Access Retinol-binding protein 4 and its potential roles in hypercholesterolemia revealed by proteomics(2015-08-28) Watcharapong Jugnam-Ang; Supitcha Pannengpetch; Patcharee sarankura-Na-Ayudhya; Chadinee Thippakorn; Chartchalerm Isarankura-Na-Ayudhya; Ratana Lawung; Virapong Prachayasittikul; Mahidol University. Faculty of Medical Technology. Department of Clinical Microbiology and Applied Technology; Mahidol University. Faculty of Medical Technology. Center for Research and InnovationEffects of hypercholesterolemia on alterations of serum proteins have not been fully elucidated. Herein, using two-dimensional gel electrophoresis (2-DE) in conjunction with LC-MS searching has successfully been carried out to investigate the change of protein expression profiles as consequences of raised blood cholesterol at different levels (normal group: total cholesterol <= 200 mg/dL; borderline high group: total cholesterol 200-239 mg/dL; and high group: total cholesterol ≥ 240 mg/dL) (n = 45). Results revealed that down-regulation of retinol-binding protein 4 (RBP4) (-2.26 fold), transthyretin (-1.25 fold) and gelsolin (-1.47 fold) was observed in the high group. Meanwhile, the other proteins such as haptoglobin, complement factor B and CD5 antigen-like protein were upregulated upto +3.24, +1.96 and +2.04 fold, respectively. Confirmation by Western blotting revealed a significant reduction of RBP4 (approximately 50%) in individual samples derived from the high group. Presumptive conclusion can be drawn that down-regulation of RBP4 might be attributable to the inflammation of adipocytes caused by the release of proinflammatory cytokines (e.g. tumor necrosis factor α and interleukin-1β) from adipose tissues. Moreover, the decrease of transthyretin might also be taken into accounts since it is known that the transthyretin usually forms complex with RBP4 to prevent glomerular filtration and excretion through the kidney. The suppressing effect on RBP4 should be potentiated by the increase of complement factor B and CD5 antigen-like protein, which rendered the adipose tissues to overwhelm the liberation of RBP4 to blood circulation by metabolic and inflammatory processes. Such inflammation could further modulate the induction of cytokine release (e.g. IL-6 and IL-1β), resulting in the synthesis of acute phase protein, in particular, haptoglobin and Creactive proteins from hepatocytes. However, the mechanism of gelsolin reduction remains unclear. Among these differentially expressed proteins, the RBP4 has been proposed as a major linkage between hypercholesterolemia, adipose tissues, liver and kidney, which is believed to be a potential biomarker for metabolic and cardiovascular disorders associated with dyslipidemia in the future. © 2015, Leibniz Research Centre for Working Environment and Human Factors. All rights reserved.Publication Open Access การประเมินผลลัพธ์ระบบการบริการโดยทีมสหสาขาวิชาชีพในคลินิกหัวใจล้มเหลว โรงพยาบาลรามาธิบดี(2562) ไวยพร พรมวงค์; อภิญญา ศิริพิทยาคุณกิจ; ขนิตฐา หาญประสิทธิ์คำ; Waiyaporn Promwong; Apinya Siripitayakunkit; Kanitha Hanprasitkam; มหาวิทยาลัยมหิดล. คณะแพทยศาสตร์โรงพยาบาลรามาธิบดี. โรงเรียนพยาบาลรามาธิบดีof the sample re-visited the emergency room, but three persons with HF were re-hospitalized. Regarding self-care behaviors, it was found that most participants were able to regulate volume overload, exercise daily or at least 3-5 days per week, and take