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Item Metadata only Natural Polyphenol Corilagin Enhances Osteogenesis and Chondrogenesis Differentiation of Mesenchymal Stem Cells: Implications for Bone and Cartilage Regeneration(2026-01-01) Kulsirirat T.; Honsawek S.; Takeda-Morishita M.; Sathirakul K.; Kulsirirat T.; Mahidol UniversityCorilagin is a hydrolyzable ellagitannin and naturally occurring polyphenolic compound widely distributed in medicinal plants. It is also present in longan (Dimocarpus longan), known as lumyai in Thailand, a subtropical fruit extensively cultivated... across China and Southeast Asia. Corilagin has been reported to exhibit strong antioxidant, anti-inflammatory, hepatoprotective, and anticancer activities through modulation of multiple cellular signaling pathways. However, despite these well-establishedItem Metadata only กรรมวิธีการเตรียมสารสกัดจากเมล็ดลำไย, องค์ประกอบที่มีสารสกัดจากเมล็ดลำไยที่เตรียมโดยกรรมวิธีนั้นและการใช้องค์ประกอบดังกล่าวสมเด็จพระเจ้าลูกเธอ เจ้าฟ้าจุฬาภรณ์วลัยลักษณ์ อัครราชกุมารี; มหาวิทยาลัยมหิดล. คณะวิทยาศาสตร์; มหาวิทยาลัยมหิดล. คณะแพทยศาสตร์ศิริราชพยาบาลItem Metadata only Erratum: Correction: Kulsirirat et al. Natural Polyphenol Corilagin Enhances Osteogenesis and Chondrogenesis Differentiation of Mesenchymal Stem Cells: Implications for Bone and Cartilage Regeneration. Molecules 2026, 31, 194 (Molecules (Basel, Switzerland) (2026) 31 1 PII: 412 DOI: 10.3390/molecules31010194.)(2026-01-26) Kulsirirat T.; Honsawek S.; Takeda-Morishita M.; Sathirakul K.; Kulsirirat T.; Mahidol UniversityIn the original publication [...].Publication Metadata only Identification and quantification of polyphenolic compounds in longan (Euphoria longana Lam.) fruit(2005-03-09) Nuchanart Rangkadilok; Luksamee Worasuttayangkurn; Richard N. Bennett; Jutamaad Satayavivad; Chulabhorn Research Institute; Quadram Institute Bioscience; Mahidol Universityof longan fruit, and the major components were identified as gallic acid, corilagin (an ellagitannin), and ellagic acid. A high-through-put reversed phase HPLC method was developed to determine the content of these three compounds in different parts... of the longan fruit and among different cultivars. The analyses showed that there was a large variation in the contents of gallic acid, corilagin, and ellagic acid in different plant tissues and cultivars. Seed contained the highest levels of the three phenolicsPublication Metadata only In vitro antifungal activities of longan (Dimocarpus longan Lour.) seed extract(2012-04-01) Nuchanart Rangkadilok; Songsak Tongchusak; Rachasak Boonhok; Sansanee C. Chaiyaroj; Varaporn B. Junyaprasert; Waranun Buajeeb; Jaratluck Akanimanee; Thida Raksasuk; Theeralaksna Suddhasthira; Jutamaad Satayavivad; Chulabhorn Research Institute; Chulabhorn Graduate Institute; Mahidol Universityactivity followed by corilagin and gallic acid, respectively. Ellagic acid inhibited Candida parapsilosis and C. neoformans more effectively than Candida krusei and also some Candida albicans clinical strains. Baidam cultivar possessed higher antifungal... activity (MIC = 500-4000 μg/ml) as it contained higher contents of ellagic acid and gallic acid than Edor (MIC = 1000-8000 μg/ml). For antibacterial activity, only corilagin and gallic acid possessed weak to moderate inhibitory effects againstPublication Metadata only Evaluation of free radical scavenging and antityrosinase activities of standardized longan fruit extract(2007-02-01) Nuchanart Rangkadilok; Somkid Sitthimonchai; Luksamee Worasuttayangkurn; Chulabhorn Mahidol; Mathuros Ruchirawat; Jutamaad Satayavivad; Chulabhorn Research Institute; Mahidol University, and in particular antioxidant activities. Longan seeds are found to contain high levels of some beneficial polyphenolic compounds such as corilagin, gallic acid and ellagic acid. The present study examined the free radical scavenging activity of longan seed extract... by using three different assay methods. Longan extracts contained corilagin ranging from zero to 50.64 mg/g DW, gallic acid from 9.18 to 23.04 mg/g DW, and ellagic acid from 8.13 to 12.65 mg/g DW depending on the cultivars. Dried longan seed extractsPublication Metadata only Isolation and characterization of ellagitannins as the major polyphenolic components of Longan (Dimocarpus longan Lour) seeds(2012-05-01) Yuttana Sudjaroen; William E. Hull; Gerhard Erben; Gerd Würtele; Supranee Changbumrung; Cornelia M. Ulrich; Robert W. Owen; German Cancer Research Center; Mahidol Universitypalmitic (35%) and oleic (28%) acids. The polyphenolic fraction (80.90 g/kg dry weight) was dominated by ellagic acid (25.84 g/kg) and the known ellagitannins corilagin (13.31 g/kg), chebulagic acid (13.06 g/kg), ellagic acid 4-O-α-l-arabinofuranoside (9... acid and corilagin. © 2011 Elsevier Ltd. All rights reserved.Item Metadata only Hypoglycemic activities of the extract of Thai traditional herbal formula used in Wang-Nam-Yen Hospital(Mahidol University. Mahidol University Library and Knowledge Center, 2023) Kullacha Chayarop; Rungravi Temsiririrkkul; Penchom Peungvicha; Yuvadee Wongkrajang; Wongsatit Chuakul; Piyanuch Rojsangawas significantly increased after incubated with the extract (50-200 μg/ml). The compounds responsible for adipocyte glucose uptake stimulatory activity were corilagin, gallic acid, ellagic acid. The amount of these compounds in the extract could be simultaneously...เพิ่มการนำน้ำตาลกลูโคสเข้าสู่เซลล์เพาะเลี้ยง HepG2 และ 3T3-L1 adipocyte ได้อย่างมีนัยสำคัญ จากการทดลอง พบว่าสารสำคัญที่ออกฤทธิ์เพิ่มการนำกลูโคสเข้าสู่เซลล์ 3T3-L1 adipocyte ได้แก่ corilagin, gallic acid และ ellagic acid ดังนั้น จึงได้พัฒนำวิธีการItem Metadata only Phytochemical fingerprint analysis, anti-SARS-CoV-2, and anti-inflammatory activities of Ya Mor Harak formulation(2025-06-01) Wichian Y.; Pimrat N.; Lerdsamran H.; Sawadpongpan S.; Wichian Y.; Mahidol University. The phytochemical constituents of YMH showed seven major compounds, including gallic acid, corilagin, chebulagic acid, chebulinic acid, ellagic acid, nortiliacorinine A, and one unidentified compound (C27H22O18). The ellagic acidPublication Open Access Effect of denture cleanser containing longan-extract granules on color stability, surface roughness and hardness of a polymeric denture base material.(2011-05) Nalinee Udomchaisakul; นลินี อุดมชัยสกุล; Widchaya Kanchanavasita; วิชญ กาญจนะวสิต; Waranun Buajeeb; วรานนท์ บัวจีบ; Widchaya Kanchanavasita; วิชญ กาญจนะวสิต; Mahidol University. Faculty of Dentistry. Department of Prosthodontics; Mahidol University. Faculty of Dentistry. Department of Oral Medicine and PeriodontologyObjective: To investigate the change of color, surface roughness and surface hardness of a PMMA denture base material after immersion in solution prepared from longan-extract granules compared with denture cleanser without longan-extract granules and distilled water. Materials and methods: Circular discs of SR Triplex Hot with 30 mm. in diameter and 3 mm. in thickness (n=10) were immersed in denture cleanser containing longan-extract granules, denture cleanser without longan-extract granules or distilled water for 10 cycles of 30 minutes. Color stability, surface roughness and hardness were measured before and after immersion in those solutions for 5th and 10th cycles by using colorimeter, profilometer and Knoop hardness tester, respectively. Split-Plot ANOVA was used for analyzing the influence of denture cleanser solutions and storage times on the surface color stability, surface roughness and hardness of PMMA denture base material at a 0.05 significant level. Results and conclusions: The type of denture cleansers and immersion cycle had no influence on the color change and surface roughness. Also the result of surface hardness test of between-subjects effects (solution) and the interaction of both effects were not significant different (p>0.05), but the tests of within-subjects effects (immersion cycle) was significant different (p<0.05). So, Knoop hardness test was not modified by any solutions but decreased over time. The values of NBS ratings which is the way color changes evaluated by the human eye showed that the color change of all specimens after immersion in all solutions at 5th and 10th cycles were çtrace to slighté.