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Item Metadata only Proteomic analysis reveals beneficial effects of ellagic acid on renal cells via mitigating oxalate-induced oxidative stress and mitochondrial dysfunction(2026-04-01) Atichartsintop P.; Hadpech S.; Srinarawat W.; Muksombat N.; Peerapen P.; Thongboonkerd V.; Atichartsintop P.; Mahidol UniversityOxidative stress caused by oxalate is one of the key pathogenic factors causing renal tubular injury and kidney stone formation. Recent studies have reported that ellagic acid (a natural polyphenol abundantly present in various fruits, nuts... and medicinal plants with known antioxidant properties) has potential renoprotective effects, but with unclear molecular mechanisms. To investigate the cellular impact of ellagic acid, we applied quantitative proteomics, bioinformatics (protein interactionItem Metadata only กรรมวิธีการเตรียมสารสกัดจากเมล็ดลำไย, องค์ประกอบที่มีสารสกัดจากเมล็ดลำไยที่เตรียมโดยกรรมวิธีนั้นและการใช้องค์ประกอบดังกล่าวสมเด็จพระเจ้าลูกเธอ เจ้าฟ้าจุฬาภรณ์วลัยลักษณ์ อัครราชกุมารี; มหาวิทยาลัยมหิดล. คณะวิทยาศาสตร์; มหาวิทยาลัยมหิดล. คณะแพทยศาสตร์ศิริราชพยาบาลPublication Metadata only Isolation and characterization of ellagitannins as the major polyphenolic components of Longan (Dimocarpus longan Lour) seeds(2012-05-01) Yuttana Sudjaroen; William E. Hull; Gerhard Erben; Gerd Würtele; Supranee Changbumrung; Cornelia M. Ulrich; Robert W. Owen; German Cancer Research Center; Mahidol Universitypalmitic (35%) and oleic (28%) acids. The polyphenolic fraction (80.90 g/kg dry weight) was dominated by ellagic acid (25.84 g/kg) and the known ellagitannins corilagin (13.31 g/kg), chebulagic acid (13.06 g/kg), ellagic acid 4-O-α-l-arabinofuranoside (9...), indicating that gallates along with ellagic acid and its congeners exert their potential antioxidant effects predominantly by precipitation of proteins such as xanthine oxidase. This was confirmed for the pure compounds gallic acid, methyl gallate, ellagicPublication Metadata only Physicochemical properties and skin permeation of Span 60/Tween 60 niosomes of ellagic acid(2012-02-28) Varaporn Buraphacheep Junyaprasert; Pratyawadee Singhsa; Jiraphong Suksiriworapong; Doungdaw Chantasart; Mahidol UniversityEllagic acid (EA) is a potent antioxidant phytochemical substance which has limitation to use due to its poor biopharmaceutical properties, low solubility and low permeability. The aim of the present study was to develop niosomal formulationsItem Metadata only Ellagic acid protects type II collagen induced arthritis in rat via diminution of IKB phosphorylation and suppression IKB-NF-kB complex activation: in vivo and in silico study(2022-10-01) Khan M.A.; Rabbani G.; Kumari M.; Khan M.J.; Mahidol UniversityObjective: The present study was designed to explore the potential anti-inflammatory and anti-arthritic effects of ellagic acid (EA) in collagen-induced arthritis (CIA). Methods: CIA rats were treated with MTX (0.25 mg/kg body wt.) and EA (50 mg/kgPublication Metadata only A new ellagic acid from the leaves and twigs of irvingia malayana(2019-05-01) Thaworn Jaipetch; Sakchai Hongthong; Samreang Bunteang; Radeekorn Akkarawongsapat; Jitra Limthongkul; Chanita Napaswad; Kanoknetr Suksen; Narong Nuntasaen; Vichai Reutrakul; Chutima Kuhakarn; National Park, Wildlife and Plant Conservation Department, Thailand; Mahidol University© The Author(s) 2019 A phytochemical investigation of the leaves and twigs of Irvingia malayana led to the isolation of a new 3,3′,4′-tri-O-methylellag-ic acid-6″-acetoxy-4-O-β-glucoside (1), along with 3,3′,4′-tri-O-methylellagic acid (2), 3,3′-di...-O-methylellagic acid-4-O-β-xylo-side (3), 3,3′,4′-tri-O-methylellagic acid-4-β-O-glucoside (4), friedelin (5), friedelinol (6), methyl-3,4,5-trihydroxybenzoate (7), 5,7,4′-trihydroxyflavone-8-C-β-glucopyranoside (8), 5,7,3′,4′-tetrahydroxyflavone-8-CPublication Metadata only Identification and quantification of polyphenolic compounds in longan (Euphoria longana Lam.) fruit(2005-03-09) Nuchanart Rangkadilok; Luksamee Worasuttayangkurn; Richard N. Bennett; Jutamaad Satayavivad; Chulabhorn Research Institute; Quadram Institute Bioscience; Mahidol Universityof longan fruit, and the major components were identified as gallic acid, corilagin (an ellagitannin), and ellagic acid. A high-through-put reversed phase HPLC method was developed to determine the content of these three compounds in different parts... of the longan fruit and among different cultivars. The analyses showed that there was a large variation in the contents of gallic acid, corilagin, and ellagic acid in different plant tissues and cultivars. Seed contained the highest levels of the three phenolicsPublication Metadata only In vitro antifungal activities of longan (Dimocarpus longan Lour.) seed extract(2012-04-01) Nuchanart Rangkadilok; Songsak Tongchusak; Rachasak Boonhok; Sansanee C. Chaiyaroj; Varaporn B. Junyaprasert; Waranun Buajeeb; Jaratluck Akanimanee; Thida Raksasuk; Theeralaksna Suddhasthira; Jutamaad Satayavivad; Chulabhorn Research Institute; Chulabhorn Graduate Institute; Mahidol Universitythat longan seed exhibited antifungal activity against the opportunistic yeasts (Candida species and Cryptococcus neoformans). In contrast, longan pulp and whole fruit did not demonstrate any inhibitory effects. Ellagic acid showed the most potent antifungal... activity followed by corilagin and gallic acid, respectively. Ellagic acid inhibited Candida parapsilosis and C. neoformans more effectively than Candida krusei and also some Candida albicans clinical strains. Baidam cultivar possessed higher antifungalPublication Metadata only Evaluation of free radical scavenging and antityrosinase activities of standardized longan fruit extract(2007-02-01) Nuchanart Rangkadilok; Somkid Sitthimonchai; Luksamee Worasuttayangkurn; Chulabhorn Mahidol; Mathuros Ruchirawat; Jutamaad Satayavivad; Chulabhorn Research Institute; Mahidol University, and in particular antioxidant activities. Longan seeds are found to contain high levels of some beneficial polyphenolic compounds such as corilagin, gallic acid and ellagic acid. The present study examined the free radical scavenging activity of longan seed extract... by using three different assay methods. Longan extracts contained corilagin ranging from zero to 50.64 mg/g DW, gallic acid from 9.18 to 23.04 mg/g DW, and ellagic acid from 8.13 to 12.65 mg/g DW depending on the cultivars. Dried longan seed extractsItem Metadata only Phytochemical fingerprint analysis, anti-SARS-CoV-2, and anti-inflammatory activities of Ya Mor Harak formulation(2025-06-01) Wichian Y.; Pimrat N.; Lerdsamran H.; Sawadpongpan S.; Wichian Y.; Mahidol University. The phytochemical constituents of YMH showed seven major compounds, including gallic acid, corilagin, chebulagic acid, chebulinic acid, ellagic acid, nortiliacorinine A, and one unidentified compound (C27H22O18). The ellagic acid
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