Kittisak SriphaZlotos, Darius P.Buller, StefanMohr, KlausMahidol University. Faculty of Pharmacy. Department of Pharmaceutical Chemistry.University of Wurzburg. Pharmaceutical Institute.2010-08-092011-07-082021-05-072010-08-092011-07-082021-05-072010-08-092003Tetrahedron Letters. Vol.44, No.38 (2003),7183-6.0040-4039https://repository.li.mahidol.ac.th/handle/20.500.14594/62090In search of new lead structures for potent allosteric enhancers of antagonist binding to muscarinic M2 receptors, a novel heterocyclic ring system, 6,7,14,15-tetrahydro-15aH-azocino[1,2-a:6,5-b′]diindole, has been synthesized. The new ring skeleton was obtained from indol-2-yl-acetic acid in three steps.140273 bytesapplication/pdfengMahidol University6,7,14,15-tetrahydro-15aH-azocino[1,2-a:6,5-a']diindolenovel pentacyclic ring systemStrychnos alkaloid caracurine Vdimerization of 2-(indol-2-yl)-ethyl tosylate6,7,14,15-Tetrahydro-15aH-azocino[1,2-a:6,5-b']diindole.Synthesis of a novel pentacyclic ring systemOriginal ArticlePergamon (available from ScienceDirect)10.1016/S0040-4039(03)01796-9