Watson J.A.White N.J.Dondorp A.M.Mahidol University2023-06-182023-06-182022-01-01Trends in Parasitology Vol.38 No.1 (2022) , 11-1414714922https://repository.li.mahidol.ac.th/handle/20.500.14594/85064Driven by the malaria-protective effect of sickle-cell trait, balancing selection results in hemoglobin S equilibrium allele frequencies of between 15% and 20% in areas of high Plasmodium falciparum transmission in sub-Saharan Africa. From this we estimate that the malaria-attributable childhood mortality in the pretreatment era was between 15% and 24%.Immunology and MicrobiologyShort SurveySCOPUS10.1016/j.pt.2021.10.0052-s2.0-851204636971471500734862145