Kumutnart ChanprapaphJutamas TankunakornChanikarn Patcharapojanart2024-01-102024-01-10202020202024Thematic Paper (M.Sc. (Medicine))--Mahidol University, 2020https://repository.li.mahidol.ac.th/handle/20.500.14594/92137Medicine (Mahidol University 2020)Systemic lupus erythematosus (SLE) is an autoimmune disorder which has been linked to multifactorial aspects such as genetic susceptibility infection and environmental factor. Vitamin D deficiency is one of the compelling factors that are currently gaining attention. This review summarizes the effect of hypovitaminosis D on SLE development and recommendations for vitamin D supplements in SLE. Existing data indicates high prevalence of vitamin D deficiency among lupus patients. A number of studies show that hypovitaminosis D may contribute to lupus pathogenesis and higher disease activity. Although no available consensus exists regarding vitamin D status and treatment for immunological purposes in SLE, the recent studies show that vitamin D supplementation tends to improve disease severity of SLE patients without any serious side effects reported. Consequently, vitamin D treatment can be given in lupus patients based on the individual profile of each patient and updated current evidence-based data.vii, 31 leaves : ill.application/pdfengผลงานนี้เป็นลิขสิทธิ์ของมหาวิทยาลัยมหิดล ขอสงวนไว้สำหรับเพื่อการศึกษาเท่านั้น ต้องอ้างอิงแหล่งที่มา ห้ามดัดแปลงเนื้อหา และห้ามนำไปใช้เพื่อการค้าVitamin DVitamin D DeficiencySystemic lupus erythematosusLupus erythematosusMaster ThesisMahidol University